Allergy Asthma Respir Dis.  2018 Jul;6(4):229-233. 10.4168/aard.2018.6.4.229.

Ecthyma gangrenosum and agranulocytosis in a previously healthy 12-month-old girl: Report of 1 case with a literature review

Affiliations
  • 1Department of Pediatrics, Soonchunhyang Unversity College of Medicine, Cheonan, Korea. pjstable@schmc.ac.kr
  • 2Department of Dermatology, Soonchunhyang Unversity College of Medicine, Cheonan, Korea.
  • 3Department of Orthopedic Surgery, Soonchunhyang Unversity College of Medicine, Cheonan, Korea.
  • 4Department of Clinical Laboratory Medicine, Soonchunhyang Unversity College of Medicine, Cheonan, Korea.
  • 5Department of Emergency Medicine, Soonchunhyang Unversity College of Medicine, Cheonan, Korea.

Abstract

Ecthyma gangrenosum (EG) is a rare skin manifestation which starts with a maculopapular eruption and followed by a necrotic ulcer covered with black eschar. EG usually occurs in immunosuppressed patients with Pseudomonas aeruginosa sepsis. We present a previously healthy 12-month-old girl with EG by P. aeruginosa and agranulocytosis due to influenza A and then rhinovirus infection, without bacteremia. It is important for allergists to culture wound and differentiate EG from other skin disorders including Tsutsugamushi disease and initiate appropriate empiric antipseudomonal antibiotic treatment, and to evaluate for possible immunodeficiency, even in a healthy child.

Keyword

Ecthyma gangrenosum; Agranulocytosis; Pseudomonas aeruginosa

MeSH Terms

Agranulocytosis*
Bacteremia
Child
Ecthyma*
Female*
Humans
Infant*
Influenza, Human
Pseudomonas aeruginosa
Rhinovirus
Scrub Typhus
Sepsis
Skin
Skin Manifestations
Ulcer
Wounds and Injuries
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