Investig Clin Urol.  2017 Nov;58(6):434-439. 10.4111/icu.2017.58.6.434.

Establishment of Korean prostate cancer database by the Korean Urological Oncology Society

• Ahn H
• Kim HJ
• Jeon SS
• Kwak C
• Sung GT
• Kwon TG
• Park JY
• Paick SH

• KMID: 2414771
• DOI: http://doi.org/10.4111/icu.2017.58.6.434

Abstract

PURPOSE
Despite the necessity, to date, no detailed database of prostate cancer, especially one that includes clinicopathological data, has been created in Korea. For that reason, the Korean Urological Oncology Society (KUOS) decided to create the Korean Prostate Cancer Database (KPCD).
MATERIALS AND METHODS
The KPCD program was introduced in 2010. After considering regional distribution, a total of 20 hospitals participated in the KPCD. The Database consists of 4 domains (demographic, pretreatment, treatment, and follow-up data) and 135 variables.
RESULTS
In total, 7,608 men with prostate cancer between 2000 and 2010 were registered in the KPCD. The mean age at the time of diagnosis was 67.6±7.7 years. The mean PSA at diagnosis was 74.0±366.9 ng/mL, and the proportions of patients with Gleason scores of ≤6, 7, and 8-10 were 37.0%, 26.7%, and 34.2%, respectively. At diagnosis, 62.3% of the patients had localized tumors, 14.6% had regional, 12.8% had distant, and 10.4% cases were from unknown diseases. With regards to the initial treatment modality employed, 1.3% of patients were managed with active surveillance, 62.1% underwent surgery, 4.3% underwent radiotherapy, 27.1% had androgen deprivation therapy, and 5.2% underwent unknown therapies. The 5-year cancer-specific survival rate of patients in the KPCD was 98.6% in the localized stage, 94.8% in the regional stage, 74.7% in the distant stage, and 86.9% in the unknown stage.
CONCLUSIONS
The KUOS created a relatively successful database of patients with prostate cancer in Korea. The KPCD will continue to improve the availability of data regarding prostate cancer.

Keyword

Database; Korea; Prostatic neoplasms

MeSH Terms

Diagnosis
Follow-Up Studies
Humans
Korea
Male
Prostate*
Prostatic Neoplasms*
Radiotherapy
Survival Rate

Figure

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  Fig. 1 Five- and 10-year cancer-specific survival (CSS; A) and overall survival (OS; B) rates of patients included from the KPCD. Korean Prostate Cancer Database.

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  Fig. 2 Cancer-specific survival (A) and overall survival (B) of patients included in the Korean Prostate Cancer Database based on the stage at diagnosis.

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