Ann Dermatol.  2018 Apr;30(2):255-257. 10.5021/ad.2018.30.2.255.

A Case of Primary Cutaneous Aggressive Epidermotropic CD8+ Cytotoxic T-Cell Lymphoma

Affiliations
  • 1Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea. khcho@snu.ac.kr

Abstract

No abstract available.


MeSH Terms

Lymphoma, T-Cell*
T-Lymphocytes*

Figure

  • Fig. 1 Widespread eruption of erythematous plaques, and papulonodular lesions involving central ulcers on upper body and face.

  • Fig. 2 (A) Lichenoid and strongly epidermotropic infiltration of atypical lymphoid cells in epidermis and upper dermis (H&E, ×100). (B) Epidermal spongiosis and necrosis with scattered lymphocytes accompanying a perivascular distribution in dermis (H&E, ×400). (C) Immunohistochemistry indicating that the tumor cells were positive for CD3 (×100) and (D) CD8 (×100).


Reference

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3. Kato K, Oh Y, Takita J, Gunji Y, Kobayashi C, Yoshimi A, et al. Molecular genetic and cytogenetic analysis of a primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphoma. Int J Hematol. 2016; 103:196–201.
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