Ann Dermatol.  2018 Apr;30(2):234-236. 10.5021/ad.2018.30.2.234.

Atypical Proliferative Nodule with Melanocytic Intraepidermal Pagetoid Spreading Arising within a Congenital Melanocytic Nevus in a Pregnant Woman

• Moon HR
• Lee MH
• Won CH
• Chang SE
• Lee MW
• Choi JH
• Moon KC

• KMID: 2414690
• DOI: http://doi.org/10.5021/ad.2018.30.2.234

Abstract

No abstract available.

MeSH Terms

Female
Humans
Nevus, Pigmented*
Pregnant Women*

Figure

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  Fig. 1 Multiple papules and nodules arising in a black-colored, slightly elevated plaque on the right posterior thigh during pregnancy.

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  Fig. 2 (A) Cellular proliferation showing no deep infiltration (H&E, ×40). (B) Proliferation of melanocytes in the background of a melanocytic nevus (H&E, ×100). (C) Intraepidermal pagetoid proliferation of melanocytes (H&E, ×200). (D) Ki-67 immunostaining showing high positivity in around 10% of the melanocytes (Ki-67, ×200). (E) Proliferation of melanocytes showing positivity for estrogen receptor (estrogen receptor β, ×40).

Reference

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