Ann Dermatol.  2018 Apr;30(2):222-225. 10.5021/ad.2018.30.2.222.

Eccrine Poroma with Rapid Growth during Pregnancy: A Case Report and Review of the Literature

• Moon J
• Lee JS
• Park HS
• Yoon HS
• Cho S

• KMID: 2414686
• DOI: http://doi.org/10.5021/ad.2018.30.2.222

Abstract

Eccrine poroma is a benign solitary tumor with acrosyringeal differentiation that usually occurs on the sole or either side of the foot. Rapid growth of eccrine poroma during pregnancy has rarely been reported. We demonstrate a unique case of a 37-year-old pregnant woman who suffered from enlarged eccrine poroma on her left palm, which was tiny for 10 years but suddenly grew to a size of bean-sized reddish brown colored, pedunculated mass during pregnancy. The patient denied a previous history of trauma or infection to the lesion. Histopathologic findings with a shave biopsy were consistent with eccrine poroma. After the tumor was completely removed by the shave biopsy, no recurrence was noted for 5 months.

Keyword

Eccrine glands; Growth; Poroma; Pregnancy

MeSH Terms

Adult
Biopsy
Eccrine Glands
Female
Foot
Humans
Poroma*
Pregnancy*
Pregnant Women
Recurrence

Figure

• 

  Fig. 1 A 1×1-cm-sized, rapidly proliferating, protruding nodule with pruritus and pain on the left palm.

• 

  Fig. 2 (A) A thick epithelial mass consisted of tumor cells that deeply infiltrate into dermis (H&E, ×40). (B) The monomorphous basophilic tumor cells with clear cytoplasm in an uneven distribution (H&E, ×400). (C) The tumor cells stained focally positive for epithelial membrane antigen (×400) and (D) with periodic acid-Schiff stain which indicates glycogen (×400).

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