J Gynecol Oncol.  2017 Jul;28(4):e29. 10.3802/jgo.2017.28.e29.

Sentinel lymph node mapping with indocyanine green in vaginal cancer

Affiliations
  • 1Department of Obstetrics and Gynecology, Institute of Women's Medical Life Science, Yonsei University College of Medicine, Seoul, Korea. nahmej6@yuhs.ac

Abstract


OBJECTIVE
Sentinel lymph node (SLN) mapping is being adapted to gynecologic cancer. Higher SLN mapping rates were reported with indocyanine green (ICG) compared to other dyes. The aim of this film is to share our experience of SLN mapping with ICG in vaginal cancer.
METHODS
A 40 year-old woman was diagnosed with squamous cell vaginal cancer. About 1.5 cm-sized tumor was located on the posterior vaginal fornix. Preoperatively she was assumed to be stage I vaginal cancer. Beginning of surgery, we performed SLN mapping by ICG injection into 3- and 9-o'clock positions of the vaginal tumor. Concentrated in 1.25 mg/mL, 1 mL of ICG solution was injected into deep stroma and another 1 mL submucosally in both sides. Bilateral SLN identification and lymphadenectomy were done. Afterward, laparoscopic Type C1 Querleu-Morrow radical hysterectomy with vaginectomy was done. A fluorescence endoscope produced by KARL STORZ (Tuttlingen, Germany) was used for ICG detection.
RESULTS
To our knowledge, this is the first film report performing SLN mapping with ICG in vaginal cancer. The mapping was successful and we were able to recognize SLN of vaginal cancer. SLNs were located in the bilateral obturator fossa. According to the pathologic diagnosis, the mass size was 15 mm and invasion depth was 1 mm. Subvaginal tissue involvement and pelvic wall extension were absent. Resection margin of the vagina was free from carcinoma. No lymph node metastasis was reported including the bilateral SLNs.
CONCLUSION
For vaginal cancer, SLN mapping can be applied by injecting ICG into the bilateral sides of the vaginal tumor.

Keyword

Vaginal diseases; Neoplasms; Sentinel Lymph Node; Indocyanine Green

MeSH Terms

Adult
Carcinoma, Squamous Cell/*pathology/surgery
Coloring Agents
Female
Humans
Indocyanine Green
Laparoscopy
*Lymph Node Excision
Optical Imaging
Sentinel Lymph Node/*diagnostic imaging/pathology/surgery
Vaginal Neoplasms/*pathology/surgery
Coloring Agents
Indocyanine Green
Full Text Links
  • JGO
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr