J Vet Sci.  2016 Sep;17(3):407-411. 10.4142/jvs.2016.17.3.407.

Reproductive ability of a cloned male detector dog and behavioral traits of its offspring

• Lee JH
• Kim GA
• Kim RS
• Lee JS
• Oh HJ
• Kim MJ
• Hong DK
• Lee BC

• KMID: 2413142
• DOI: http://doi.org/10.4142/jvs.2016.17.3.407

Abstract

In 2007, seven detector dogs were produced by somatic cell nuclear transfer using one nuclear donor dog, then trained and certified as excellent detector dogs, similar to their donor. In 2011, we crossed a cloned male and normal female by natural breeding and produced ten offspring. In this study, we investigated the puppies' temperaments, which we later compared with those of the cloned parent male. The results show that the cloned male had normal reproductive abilities and produced healthy offspring. All puppies completed narcotic detector dog training with a success rate for selection of 60%. Although the litter of cloned males was small in this study, a cloned male dog bred by natural mating produced puppies that later successfully completed the training course for drug detection. In conclusion, cloning an elite dog with superior genetic factors and breeding of the cloned dog was found to be a useful method to efficiently procure detector dogs.

Keyword

behavioral traits; cloned dog; drug detection dog; reproductive normality

MeSH Terms

Animals
*Behavior, Animal
Cloning, Organism/*veterinary
Dogs/*physiology/psychology
Male
Nuclear Transfer Techniques/veterinary
*Reproduction
*Temperament

Figure

• 

  Fig. 1 Birth of puppies. (A) Hormonal change in a female dog from estrus to delivery. The square indicates the fertile period of a female dog. While in these periods, she stayed with a male cloned dog in a room. The arrow indicates the delivery time. (B) Appearance of puppies at 1 day after delivery.

• 

  Fig. 2 Mature appearance of F1 (P1–P10) produced by breeding a male cloned dog and a female dog. F1 developed without health problems until the end of training course. The image was taken at 2 years of age.

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