Clin Mol Hepatol.
2017 Jun;23(2):184-187. 10.3350/cmh.2016.0035.
Development of autoimmune hepatitis in a psoriasis patient without immunosuppressive therapy
- Affiliations
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- 1Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Korea. galleonok@hanmail.net
- 2Department of Radiology, Gyeongsang National University School of Medicine, Jinju, Korea.
- 3Department of Pathology, Gyeongsang National University School of Medicine, Jinju, Korea.
- KMID: 2413123
- DOI: http://doi.org/10.3350/cmh.2016.0035
Abstract
- We present a case of a 65-year-old man with psoriasis who developed autoimmune hepatitis (AIH) without receiving immunosuppressive therapy with either anti-tumor necrosis factor-α or methotrexate. The AIH had completely resolved at 2 months after prednisolone and azathioprine therapy. This case confirms the need to consider AIH in psoriasis patients who experience new elevations in liver enzymes. To our knowledge, this is first description of the development of AIH in an immunosuppressant-naïve patient with psoriasis.
Keyword
MeSH Terms
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Aged
Alanine Transaminase/analysis
Aspartate Aminotransferases/analysis
Azathioprine/therapeutic use
Drug Therapy, Combination
Hepatitis, Autoimmune/complications/diagnosis/*drug therapy
Humans
Immunosuppressive Agents/*therapeutic use
Liver/enzymology/pathology
Male
Prednisolone/therapeutic use
Psoriasis/complications/*diagnosis/drug therapy
Skin/pathology
Immunosuppressive Agents
Prednisolone
Aspartate Aminotransferases
Alanine Transaminase
Azathioprine
