Gut Liver.  2017 Mar;11(2):237-242. 10.5009/gnl16132.

Positive Glucose Breath Tests in Patients with Hysterectomy, Gastrectomy, and Cholecystectomy

• Kim DB
• Paik CN
• Kim YJ
• Lee JM
• Jun KH
• Chung WC
• Lee KM
• Yang JM
• Choi MG

• KMID: 2412190
• DOI: http://doi.org/10.5009/gnl16132

Abstract

BACKGROUND/AIMS
This study aimed to investigate the prevalence and characteristics of small intestinal bacterial overgrowth (SIBO) in patients undergoing abdominal surgeries, such as gastrectomy, cholecystectomy, and hysterectomy.
METHODS
One hundred seventy-one patients with surgery (50 hysterectomy, 14 gastrectomy, and 107 cholecystectomy), 665 patients with functional gastrointestinal disease (FGID) and 30 healthy controls undergoing a hydrogen (Hâ‚‚)-methane (CHâ‚„) glucose breath test (GBT) were reviewed.
RESULTS
GBT positivity (+) was significantly different among the surgical patients (43.9%), FGID patients (31.9%), and controls (13.3%) (p<0.01). With respect to the patients, 65 (38.0%), four (2.3%), and six (3.5%) surgical patients and 150 (22.6%), 30 (4.5%), and 32 (4.8%) FGID patients were in the GBT (Hâ‚‚)+, (CHâ‚„)+ and (mixed)+ groups, respectively (p<0.01). The gastrectomy group had a significantly increased preference in GBT+ (71.4% vs 42.0% or 41.1%, respectively) and GBT (Hâ‚‚)+ (64.3% vs 32.0% or 37.4%, respectively) compared with the hysterectomy or cholecystectomy groups (p<0.01). During GBT, the total Hâ‚‚ was significantly increased in the gastrectomy group compared with the other groups.
CONCLUSIONS
SIBO producing H2 is common in abdominal surgical patients. Different features for GBT+ may be a result of the types of abdominal surgery.

Keyword

Glucose breath test; Cholecystectomy; Gastrectomy; Hysterectomy

MeSH Terms

Adult
Aged
Blind Loop Syndrome/diagnosis/*epidemiology/etiology
Breath Tests/methods
Case-Control Studies
Cholecystectomy/*adverse effects
Female
Gastrectomy/*adverse effects
Glucose/analysis
Humans
Hydrogen/analysis
Hysterectomy/*adverse effects
Male
Methane/analysis
Middle Aged
Postoperative Complications/diagnosis/*epidemiology/etiology
Prevalence
Hydrogen
Glucose
Methane