Int Neurourol J.  2018 Mar;22(1):58-64. 10.5213/inj.1835054.527.

Lower Urinary Tract Symptoms in Elderly Population With Multiple Sclerosis

• Chesnel C
• Charlanes
• Hentzen C
• Turmel N
• Le Breton
• Ismael SS
• Amarenco G
• for the GRAPPPA (Groupe de Recherche Appliquée à la Pelvi-Périnéologie de la Personne Agée)

• KMID: 2409728
• DOI: http://doi.org/10.5213/inj.1835054.527

Abstract

PURPOSE
The aim of this study is to compare the clinical and urodynamic characteristics of urinary disorders in multiple sclerosis (MS) patients in a geriatric population with a nongeriatric population.
METHODS
This study was conducted retrospectively between 2010 and 2016. Each patient with MS aged 65 and older was matched with 2 patients with MS aged less than 65 in sex, form of MS, and Expended Disability Status Scale (EDSS). Demographic data, urinary symptoms, treatment, quality of life, repercussion of lower urinary tract symptoms on daily life activities and psychological state and urodynamic parameters were collected. Differences between the 2 populations were evaluated using Student test, chi-square, or Fischer tests.
RESULTS
Twenty-four patients with MS aged 65 and older (mean age, 69.8 years) were matched with 48 patients aged less than 65 years (mean age, 49.4 years). Maximum urethral closure pressure was lower in the elderly population than in the nongeriatric population (mean±standard deviation [SD]: 35.6±18.5 cm H < sub>2 < /sub>O vs. 78.2±52.3 cm H < sub>2 < /sub>O, P < 0.001). In the male population, there was no statistical difference in any other clinical or urodynamic endpoints. In the female population, voiding symptoms was more described in the nongeriatric population (Urinary Symptom Profile low stream: 3.4±3.5 vs. 1.7±2.4, P=0.04), geriatric population had less urinary treatment (P=0.05). LUTS had less impact on quality of life (Qualiveen: 1.4±1.0 vs. 2.1±0.9, P=0.02) on the geriatric population than in the nongeriatric of female MS patients.
CONCLUSIONS
Geriatric population of MS has few differences of urinary disorders compared to a nongeriatric population with EDSS, sex, and MS form equal. However, the psychological impact of these urinary disorders is less important in female geriatric population.

Keyword

Elderly; Lower urinary tract symptoms; Multiple sclerosis

MeSH Terms

Aged*
Female
Humans
Lower Urinary Tract Symptoms*
Male
Multiple Sclerosis*
Quality of Life
Retrospective Studies
Rivers
Urodynamics