J Korean Ophthalmol Soc.  2018 Apr;59(4):319-324. 10.3341/jkos.2018.59.4.319.

Treatment Outcome of Wound Infection after Cataract Surgery and Risk Factors of Treatment Failure

• Lee DK
• Moon HS
• Ji YS
• Yoon KC

• KMID: 2409679
• DOI: http://doi.org/10.3341/jkos.2018.59.4.319

Abstract

PURPOSE
To evaluate factors affecting wound infection after cataract surgery, and treatment outcomes.
METHODS
In this retrospective study, we included 20 patients (20 eyes) who experienced wound infection after cataract surgery (phacoemulsification with intraocular lens implantation) between January 2005 and January 2017. Only those who yielded positive microbial smears were selected. All patients were assigned to a "treatment success group" (remission of infection) or a "treatment failure group" (aggravation of infection or a need for surgical intervention to treat an infectious complication). The demographic, clinical and microbiological features of the two groups were compared and binary logistic regression analyses were performed to identify factors affecting treatment failure.
RESULTS
Wound infection developed at 12.25 ± 20.21 days (range 5 to 45 days) after cataract surgery. Sixteen patients developed bacterial and four developed fungal keratitis. Of the 20 patients, 13 (65.0%) were treated successfully and 7 (35.0%) were not. In univariate analyses, diabetes (p = 0.035), incisional suturing (p = 0.038), combined endophthalmitis (p = 0.001), and fungal infection (p = 0.021) were associated with treatment failure. Multivariate analyses showed that combined endophthalmitis (p = 0.001) and fungal infection (p = 0.044) were significant risk factors for treatment failure.
CONCLUSIONS
Cataract wound infection is rare but constitutes a serious complication. Combined endophthalmitis and fungal infection are associated with poor treatment outcomes.

Keyword

Cataract surgery; Complication; Infection

MeSH Terms

Cataract*
Endophthalmitis
Humans
Keratitis
Lenses, Intraocular
Logistic Models
Multivariate Analysis
Retrospective Studies
Risk Factors*
Treatment Failure*
Treatment Outcome*
Wound Infection*
Wounds and Injuries*

Figure

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  Figure 1. The frequency of wound infection after cataract surgery by year. It shows distribution of occurence in total 20 patients.

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