Ann Lab Med.  2018 Jul;38(4):371-374. 10.3343/alm.2018.38.4.371.

Effects of Cold Agglutinin on the Accuracy of Complete Blood Count Results and Optimal Sample Pretreatment Protocols for Eliminating Such Effects

Affiliations
  • 1Department of Laboratory Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. jhyooken@gmail.com
  • 2Department of Pharmacology, Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Medicine, Physician-Scientist Program, Yonsei University Graduate School of Medicine, Seoul, Korea.
  • 4Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
  • 5Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea.

Abstract

No abstract available.


MeSH Terms

Blood Cell Count*

Figure

  • Fig. 1 Summary of study design and comparative assay results. (A) Experimental flowchart of sample collection and measurements. In total, four samples were evaluated in nine measurements per analyzer. Thus, 16 samples in total were evaluated 36 times, on four different automated CBC analyzers. (B) Effects of storage temperature and duration on CBC parameters measured with the four analyzers. (C) Comparison of the four automated CBC analyzers applying two optimal protocols, which were (1) measuring CBC within 1 hour of storage at 37℃ and (2) measuring CBC after short-term storage at 4℃ for 1 hour and subsequent incubation at 37℃ for 1 hour.


Cited by  2 articles

Obtaining Reliable CBC Results in Clinical Laboratories
Seon Young Kim, Hyun Kyung Kim
Ann Lab Med. 2022;42(5):505-506.    doi: 10.3343/alm.2022.42.5.505.

Unreliable Automated Complete Blood Count Results: Causes, Recognition, and Resolution
Gene Gulati, Guldeep Uppal, Jerald Gong
Ann Lab Med. 2022;42(5):515-530.    doi: 10.3343/alm.2022.42.5.515.


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