J Cardiovasc Ultrasound.  2018 Mar;26(1):40-42. 10.4250/jcu.2018.26.1.40.

Recurrent Acute Myocardial Infarction Caused by Intra-cardiac Metastatic Undifferentiated Pleomorphic Sarcoma during Cancer Treatment

Affiliations
  • 1Division of Cardiovascular Medicine, Department of Internal Medicine, Dankook University College of Medicine, Dankook University Hospital, Cheonan, Korea. neosoo70@dankook.ac.kr
  • 2Department of Pathology, Dankook University College of Medicine, Cheonan, Korea.

Abstract

No abstract available.

Keyword

Coronary occlusion; Sarcoma; Cardiac tumor

MeSH Terms

Coronary Occlusion
Heart Neoplasms
Myocardial Infarction*
Sarcoma*

Figure

  • Fig. 1 Computed tomography and coronary angiography. A: Initial chest computed tomography showed a large, infiltrative, and heterogeneously soft tissue mass at the left axilla (white arrow). There was no definite mass in the left atrium (black arrow). B: Coronary angiography showed the total occlusion of the distal left anterior descending artery (white arrow). C: The aspirated tissue material appeared as mucoid and whitish debris. D: The final coronary angiography showed that flow had been completely restored (black arrow).

  • Fig. 2 Echocardiography. A: Echocardiography showed a huge mass with heterogeneous echogenicity in the left atrium affecting through the mitral valve leaflet before six months ago, at the time of pembrolizumab treatment (white arrow). B: The left atrium tumor mass was significantly decreased at the time of admission in the echocardiography (white arrow head).

  • Fig. 3 Pathology findings. A: The primary axillary tumor was cytologically compatible with undifferentiated pleomorphic sarcoma that focally showed discohesive and relatively monotonous round cell components (black arrows) (H&E, × 200). B: The coronary embolus tissues showed similar round cell morphology and a few scattered pleomorphic giant cells (H&E, × 400). C: The tumor cells were diffusely immunoreactive with vimentin, a representative mesenchymal marker (ABC, × 200). H&E: hematoxylin and eosin.


Reference

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