Infect Chemother.  2010 Apr;42(2):122-126.

Early Extracorporeal Membrane Oxygenation in a Patient with Pandemic Influenza (H1N1 2009) and Acute Respiratory Distress Syndrome

• Lee KH
• Yie K
• Oh WS
• Ryu SW
• Chon SB
• Lee SJ

Abstract

Despite advanced technologies in intensive care, pandemic influenza (H1N1 2009) can rapidly progress to acute respiratory distress syndrome (ARDS) and cause death in a small subset of patients. Extracorporeal membrane oxygenation (ECMO) is expected to provide adequate gas exchange, to reduce ventilator-induced lung injury and, eventually, to improve outcome in these patients. A previously healthy, young female received mechanically ventilatory support because of rapidly progressive respiratory failure caused by 2009 H1N1 influenza. As she failed to respond to high ventilatory support, ECMO was instituted at 6 hours after admission. We describe detailed course of case and literature review on ECMO, helping physicians make a decision to initiate ECMO in patients with influenza-related ARDS.

Keyword

Pandemic influenza (H1N1 2009); Acute respiratory distress syndrome; Extracorporeal membrane oxygenation

MeSH Terms

Critical Care
Extracorporeal Membrane Oxygenation
Female
Humans
Influenza, Human
Pandemics
Respiratory Distress Syndrome, Adult
Respiratory Insufficiency
Ventilator-Induced Lung Injury

Figure

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  Figure 1 Chest radiography at the 1st (A) and the 4th day (B) of admission.

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  Figure 2 High resolution computed tomography of the chest at the 2nd (A) and the 7th day (B) of admission.

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