J Korean Soc Radiol.  2017 Sep;77(3):197-200. 10.3348/jksr.2017.77.3.197.

Solitary Bladder Metastasis of Prostate Cancer Mimicking Bladder Submucosal Tumor: A Case Report

  • 1Department of Radiology, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea. shinshlee@naver.com
  • 2Department of Urology, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea.
  • 3Department of Pathology, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea.


Prostate cancer is one of the most common causes of secondary cancer to the bladder. There have been few reports about distant metastasis to the bladder from primary prostate cancer, since secondary involvement of the urinary bladder in prostate cancer is most often by direct invasion. Metastatic prostate cancer to the bladder is often mistaken for other primary bladder tumors. Here, we report a case of solitary metastatic prostatic cancer to the bladder, which was previously misdiagnosed as a submucosal tumor of the bladder.

MeSH Terms

Neoplasm Metastasis*
Prostatic Neoplasms*
Urinary Bladder Neoplasms
Urinary Bladder*


  • Fig. 1 A Solitary bladder metastasis of prostate cancer in a 75-year-old man. A. The coronal T2-weighted MR image shows a homogeneously moderate hypointense mass in the right lobe of the prostate gland (arrowheads), and a 1.1 cm sized submucosal tumor with heterogeneously high signal intensity at the right posterior wall of the urinary bladder (arrow). There is no evidence of connection between the two lesions. B. Axial apparent diffusion coefficient maps show a heterogeneously moderate hypointense tumor in the urinary bladder (arrow), and a markedly hypointense tumor in the right lobe of the prostate gland (arrowheads). C. Axial T1-weighted MR image shows an isointense tumor with an internal hyperintense portion in the urinary bladder (arrow). D. Contrasted enhanced fat-saturated T1-weighted MR image shows a heterogeneous enhancing tumor in the urinary bladder (arrow). E. Cystoscopy reveals a small submucosal tumor in the right posterior wall of the urinary bladder (arrows). F. Transurethral resection of the bladder tumor histopathologically confirms it as a metastatic prostate adenocarcinoma, which forms multiple cribriform irregular nests infiltrating the muscle layer of the urinary bladder (hematoxylin-eosin stain, original magnification × 100). The tumor cells are strongly positive to prostate-specific antigen (immunohistochemical stain, original magnification × 100).


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