J Korean Ophthalmol Soc.  2018 Feb;59(2):153-158. 10.3341/jkos.2018.59.2.153.

The Effect of Refractive Power on Retinal Volume Measurement Using Spectral Domain Optical Coherence Tomography

• Lee M
• Nam K
• Lee S
• Lee S

• KMID: 2403808
• DOI: http://doi.org/10.3341/jkos.2018.59.2.153

Abstract

PURPOSE
To investigate the change of retinal volume according to anterior segment refractive power using contact lens by spectral domain optical coherence tomography (SD-OCT).
METHODS
The retinal volume was measured using a SD-OCT (Heidelberg retinal angiography Spectralis + OCT, Heidelberg Engineering, Heidelberg, Germany) in 60 subjects without any underlying disease. The same examiner performed a 31-section macular volume-scan at 240 µm intervals, re-measured the same area by changing the refractive power of the anterior segment by wearing soft contact lenses of +6.0 diopters and −6.0 diopters. By using the ImageJ software to calculate the cross-sectional area and of the cross-sectional area and the volume was measured.
RESULTS
The mean age of the participants was 25.6 ± 1.5 years and the mean axial length was 25.7 ± 1.57 mm. The volume of the posterior pole retina measured without the contact lens was 13.48 ± 0.05 and the mean volume of the retina measured with +6.0 diopter and −6.0 diopter contact lens in the same patient was 13.47 ± 0.07 mm³ and 13.48 ± 0.05 respectively. The mean volume was significantly lower(p = 0.036) in the measurement with the +6.0 diopter lens than in the measurement without the lens, and the mean volume was significantly higher in the measurement with the +6.0 diopter lens (p = 0.042). The change in retinal thickness was increased with longer axial length (r = 0.32, p < 0.05), but the central foveal thickness did not correlate with anterior corneal power (p = 0.463).
CONCLUSIONS
The volume of the retina measured using the SD-OCT is affected by the refractive power of the anterior segment and the axial length. Therefore, it is necessary to consider the change of refractive index because it can change the retinal volume measured by SD-OCT.

Keyword

Anterior segment power; Retinal volume; Spectral domain optical coherence tomography (SD-OCT)

MeSH Terms

Angiography
Contact Lenses, Hydrophilic
Humans
Refractometry
Retina
Retinaldehyde*
Tomography, Optical Coherence*
Retinaldehyde

Figure

• 

  Figure 1 Measurement of posterior pole retinal volume. (A) 31 sections of macular transverse volume scan and 8 × 7.2 mm of calculated area (red box). (B) The area to be measured was set by correcting the borderline error of the cross - sectional area from the basement membrane to the internal limiting memebrane in the cross section of the retina. (C) The width of the retina set (B) is shown in a schematic diagram and the width of the set area was measured using the Image j program (displayed as a red line).

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