Asian Oncol Nurs.  2017 Dec;17(4):220-228. 10.5388/aon.2017.17.4.220.

Factors Influencing Health Related Quality of Life in Adult Survivors of Haematopoietic Stem Cell Transplantation

• Kwon H
• Ryu E

• KMID: 2401637
• DOI: http://doi.org/10.5388/aon.2017.17.4.220

Abstract

PURPOSE
The aim of the study is to evaluate the health-related quality of life, psychological symptoms, distress, and sense of coherence in adult haematopoietic stem cell transplantation survivors.
METHODS
Fifty two survivors completed four questionnaires after the transplantation. The questionnaires were the Functional Assessment of Cancer Therapy-BMT Scale, the National Cancer Center Psychological Symptom Inventory, the Distress Thermometer, and the Sense of Coherence scale.
RESULTS
Quality of life was positively correlated with sense of coherence, whereas sense of coherence was negatively correlated with all psychological symptoms and distress. Hierarchical regression analyses revealed that sense of coherence was the only significant predictor of quality of life after controlling for sex and age at transplantation. Model 2 explained 33.2% of the total variance of quality of life.
CONCLUSION
Supporting patients towards improving comprehensibility, manageability and meaningfulness, the three components of sense of coherence, may be beneficial and improve outcomes. Individually pre-transplant and post-transplant assessments of sense of coherence may be of clinical importance, in order to identify patients with unmet needs and to provide rolonged support.

Keyword

Hematopoietic Stem Cell Transplantation; Quality of Life; Symptom Assessment; Distress; Sense of Coherence

MeSH Terms

Adult*
Hematopoietic Stem Cell Transplantation
Humans
Quality of Life*
Sense of Coherence
Stem Cell Transplantation*
Stem Cells*
Survivors*
Symptom Assessment
Thermometers