Nat Prod Sci.  2017 Dec;23(4):253-257. 10.20307/nps.2017.23.4.253.

Chemical Constituents of Nelumbo nucifera Seeds

• Rho T
• Yoon KD

• KMID: 2401576
• DOI: http://doi.org/10.20307/nps.2017.23.4.253

Abstract

The phytochemical study for the extract of Nelumbo nucifera (Nymphaceae) seeds has led to the isolation of ten compounds including five simple phenolic compounds, two indole derivatives, a flavonoid glycoside, two abscisic acid derivatives. The interpretation of 1D and 2D NMR and ESI-Q-TOF-MS spectroscopic data revealed the chemical structures of isolates to be p-hydroxybenzoic acid (1), protocatechuic acid (2), (E)-p-coumaric acid (3), (E)-ferulic acid (4), (E)-sinapate-4-O-β-D-glucopyranoside (5), tryptophan (6), 3-indoleacetic acid (7), isoschaftoside (8), dihydrophaseic acid (9), dihydrophaseic acid 3"²-O-β-D-glucopyranoside (10). To the best of our knowledge, 1 - 5 and 7 were identified for the first time from N. nucifera seeds, and the presence of dihydrophaseic acid (9) and its glucoside (10) were demonstrated secondly in this plant.

Keyword

Nelumbo nucifera; Seeds; Nymphaceae; Phytochemical study

MeSH Terms

Abscisic Acid
Nelumbo*
Phenol
Plants
Tryptophan
Abscisic Acid
Phenol
Tryptophan

Figure

• 

  Fig. 1. The chemical structures of 1 – 10 from Nelumbo nucifera seeds.

Reference

References

(1). The Compilation Committee of Pharmacognosy Textbook. Pharmacognosy; Dong-Myeung press: Korea,. 2015. 358–360.

(2). Sharma B. R.., Gautam L. N.., Adhikari D.., Karki R.Phytother. Res. 2017. 31:3–26.

(3). Dhakal R. C.., Rajbhandari M.., Kalauni S. K.., Awale S.., Gewali M. B. J.Nepal Chem. Soc. 2008/2009. 23:89–92.

(4). Flamini G.., Antognoli E.., Morelli I.Phytochemistry. 2001. 57:559–564.

(5). Nguyen D. H.., Zhao B. T.., Le D. D.., Kim K. Y.., Kim Y. H.., Yoon Y. H.., Ko J. Y.., Woo K. S.., Woo M. H.Nat. Prod. Sci. 2016. 22:140–145.

(6). Woo K. W.., Lee K. R.Nat. Prod. Sci. 2013. 19:221–226.

(7). Wolfram K.., Schmidt J.., Wray V.., Milkowski C.., Schliemann W.., Strack D.Phytochemistry. 2010. 71:1076–1084.

(8). Kim C. S.., Kim K. H.., Lee K. R.Nat. Prod. Sci. 2014. 20:86–90.

(9). Xie C.., Veitch N. C.., Houghton P. J.., Simmonds M. S.Chem. Pharm. Bull. 2003. 51:1204–1207.

(10). Seo J. H.., Choi Y. H.., Yoo M. Y.., Hong K. S.., Lee B. H.., Yon G. H.., Kim Y. S.., Kim Y. K.., Ryu S. Y.Kor. J. Pharmacogn. 2006. 37:290–297.

(11). Youn U. J.., Lee J.., Nam J. W.., Lee Y. J.., Seo E. K.Bull. Korean Chem. Soc. 2011. 32:4083–4085.