Pediatr Infect Vaccine.  2017 Dec;24(3):141-145. 10.14776/piv.2017.24.3.141.

Clinical Features of Kawasaki Disease with Pyuria

• Kim HJ
• Lee JY
• Choi UY
• Lee SY

• KMID: 2401388
• DOI: http://doi.org/10.14776/piv.2017.24.3.141

Abstract

PURPOSE
Clinical and laboratory features of two Kawasaki disease (KD) groups were evaluated; the patient with pyuria and those without pyuria.
METHODS
From January 2015 to December 2016, the medical records of 140 (86 males and 54 females) inpatients with KD were retrospectively analyzed.
RESULTS
Forty-eight KD patients (34.3%) presented with pyuria. KD patients with pyuria showed a higher level of C-reactive protein (CRP) and a higher proportion of elevated liver enzymes than those without pyuria. There were no differences in the proportions of unresponsiveness to intravenous immunoglobulin and coronary artery lesions between the two groups. Six KD patients (12.5%) with pyuria underwent a renal imaging study to rule out the possibility of a urinary tract infections. Thirty-two KD patients (66.7%) with pyuria received treatment with antibiotics in addition to the standard treatment for KD.
CONCLUSIONS
KD patients with pyuria showed a higher level of CRP and elevated levels of liver enzymes than those without pyuria. These findings suggest that KD patients with pyuria have more severe systemic inflammation than those without pyuria.

Keyword

Mucocutaneous lymph node syndrome; Pyuria; Fever; Child

MeSH Terms

Anti-Bacterial Agents
C-Reactive Protein
Child
Coronary Vessels
Fever
Humans
Immunoglobulins
Inflammation
Inpatients
Liver
Male
Medical Records
Mucocutaneous Lymph Node Syndrome*
Pyuria*
Retrospective Studies
Urinary Tract Infections
Anti-Bacterial Agents
C-Reactive Protein
Immunoglobulins

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