Yeungnam Univ J Med.
2017 Jun;34(1):101-105. 10.12701/yujm.2017.34.1.101.
Rheumatoid arthritis accompanied by Gitelman syndrome
- Affiliations
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- 1Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center, Busan, Korea. ete@lycos.co.kr
- KMID: 2400338
- DOI: http://doi.org/10.12701/yujm.2017.34.1.101
Abstract
- Gitelman syndrome is a condition caused by a mutation of the thiazide sensitive Na-Cl cotransporter gene on the distal convoluted tubule. It results in a variety of clinical features, including hypokalemia, hypomagnesemia, hypocalciuria, and metabolic alkalosis. It is often diagnosed in asymptomatic adults presented with unexplained hypokalemia; however, it is sometimes associated with muscular cramps, numbness, fatigue, weakness, or paralysis. We experienced a case of rheumatoid arthritis accompanied by Gitelman syndrome, presented with hand tremor. We diagnosed her using renal clearance study and genetic analysis. Here, we report our experiences regarding this case along with a literature review.
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