Yeungnam Univ J Med.
2017 Jun;34(1):69-74. 10.12701/yujm.2017.34.1.69.
Follow-up of thyroid ultrasonography in patients with hemodialysis
- Affiliations
-
- 1Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Korea. jrhahm@gnu.ac.kr
- 2Institute of Health Sciences, Gyeongsang National University, Jinju, Korea.
- 3Department of Nursing, Gyeongnam National University of Science and Technology, Jinju, Korea.
- 4Division of Endocrinology and Metabolism, Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon, Korea.
- 5Department of Otolaryngology, Gyeongsang National University School of Medicine, Jinju, Korea.
- KMID: 2400331
- DOI: http://doi.org/10.12701/yujm.2017.34.1.69
Abstract
- BACKGROUND
Chronic kidney disease is considered a risk factor for thyroid nodules as well as thyroid dysfunction such as hypothyroidism. Among patients on hemodialysis, we assessed the size of thyroid nodule and goiter at baseline and 1 year later with ultrasonography.
METHODS
We prospectively selected 47 patients with hemodialysis at January 2012 and reviewed their medical records. We checked goiter and thyroid nodules at January 2012 and December 2012.
RESULTS
In the hemodialysis patients (n=47), 24 patients (51.1%) had thyroid nodules and 33 patients (70.2%) had goiter at baseline. Parathyroid hormone (PTH) was higher in patients with thyroid nodules (204.4±102.9 vs. 129.9±93.6 pg/mL, p=0.01). Thyroid ultrasonography was conducted in 29 patients after 1 year. The thickness of the thyroid isthmus increased (2.8±1.6 vs. 3.2±1.9 mm, p=0.003), but the number of nodules did not change (1.2±1.9 vs. 1.4±2.0, p=0.109). PTH was associated with the enlargement of thyroid nodules significantly through logistic regression analysis.
CONCLUSION
Thyroid goiter and nodules in hemodialysis patients were more prevalent than in the general population. PTH influenced the production of thyroid nodules in hemodialysis patients. Regular examination with thyroid ultrasonography and thyroid function test should be considered in hemodialysis patients.
