J Menopausal Med.  2017 Dec;23(3):166-171. 10.6118/jmm.2017.23.3.166.

The Effect of Foeniculum Vulgare (Fennel) on Body Composition in Postmenopausal Women with Excess Weight: A Double-blind Randomized Placebo-controlled Trial

Affiliations
  • 1Department of Obstetrics and Gynecology, Mashhad University of Medical Sciences, Mashhad, Iran.
  • 2Student Research Committee, Department of Midwifery, Nursing and Midwifery School, Mashhad University of Medical Science, Mashhad, Iran. Masumeh.ghazanfarpour@yahoo.com
  • 3Evidence-Based Care Research Centre, Mashhad University of Medical Science, Mashhad, Iran.
  • 4Abnormal Uterine Bleeding Research Center, Semnan University of Medical Sciences, Semnan, Iran.
  • 5Obstetrics and Gynecology, Women's Health Research Center, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Abstract


OBJECTIVES
The goal of this study was to evaluate the effect of fennel on body composition.
METHODS
This study is a secondary analysis of a double-blind, randomized, placebo-controlled trial. Fifty-four out of 60 patients were able to successfully complete the original study. Seven out of 54 patients were excluded because they were not overweight and obese. Thus, 47 women were included in this secondary analysis. Of these 47 women, 22 were in the fennel group and 25 were in placebo group. Body weight, body mass index (BMI) as well as fat distribution was measured at the baseline and after a three-month follow-up.
RESULTS
Comparison of fennel and placebo groups did not reveal any significant effect in terms of body weight, BMI, waist and hip circumferences and fat distribution. Also, the results of paired t-test did not variation of these parameters across groups before and after 12-week treatment.
CONCLUSIONS
Menopausal women in fennel group experienced a slight increase in body weight and fat distribution, which was not significant. Further studies with larger sample sizes are recommended to validate the results of this study.

Keyword

Body fat distribution; Body mass index; Body weight; Foeniculum; Postmenopause

MeSH Terms

Body Composition*
Body Fat Distribution
Body Mass Index
Body Weight
Female
Foeniculum*
Follow-Up Studies
Hip
Humans
Overweight
Postmenopause
Sample Size

Cited by  3 articles

Effect of Fennel on the Health Status of Menopausal Women: A Systematic and Meta-analysis
Talat Khadivzadeh, Mona Najaf Najafi, Leila Kargarfard, Masumeh Ghazanfarpour, Fatemeh Rajab Dizavandi, Imaneh Khorsand
J Menopausal Med. 2018;24(1):67-74.    doi: 10.6118/jmm.2018.24.1.67.

Foeniculum vulgare as Valuable Plant in Management of Women's Health
Mohaddese Mahboubi
J Menopausal Med. 2019;25(1):1-14.    doi: 10.6118/jmm.2019.25.1.1.

Effect of Lavender on Sleep, Sexual Desire, Vasomotor, Psychological and Physical Symptom among Menopausal and Elderly Women: A Systematic Review
Nasibeh Roozbeh, Masumeh Ghazanfarpour, Talat Khadivzadeh, Leila Kargarfard, Fatemeh Rajab Dizavandi, Khatereh Shariati
J Menopausal Med. 2019;25(2):88-93.    doi: 10.6118/jmm.18158.


Reference

1. Liu ZM, Ho SC, Chen YM, Woo J. A six-month randomized controlled trial of whole soy and isoflavones daidzein on body composition in equol-producing postmenopausal women with prehypertension. J Obes. 2013; 2013:359763.
2. Misso ML, Jang C, Adams J, Tran J, Murata Y, Bell R, et al. Differential expression of factors involved in fat metabolism with age and the menopause transition. Maturitas. 2005; 51:299–306.
3. Haarbo J, Marslew U, Gotfredsen A, Christiansen C. Post-menopausal hormone replacement therapy prevents central distribution of body fat after menopause. Metabolism. 1991; 40:1323–1326.
4. Sørensen MB, Rosenfalck AM, Højgaard L, Ottesen B. Obesity and sarcopenia after menopause are reversed by sex hormone replacement therapy. Obes Res. 2001; 9:622–626.
5. Björn I, Bäcksröm T. Drug related negative side-effects is a common reason for poor compliance in hormone replacement therapy. Maturitas. 1999; 32:77–86.
6. Rahimi R, Ardekani MR. Medicinal properties of Foeniculum vulgare Mill. In traditional Iranian medicine and modern phytotherapy. Chin J Integr Med. 2013; 19:73–79.
7. Hur MH, Kim C, Kim CH, Ahn HC, Ahn HY. The effects of inhalation of essential oils on the body weight, food efficiency rate and serum leptin of growing SD rats. J Korean Acad Nurs. 2006; 36:236–243.
8. Bae J, Kim J, Choue R, Lim H. Fennel (Foeniculum vulgare) and Fenugreek (Trigonella foenum-graecum) tea drinking suppresses subjective short-term appetite in overweight women. Clin Nutr Res. 2015; 4:168–174.
9. Kim SJ, Kim KS, Shin SU, Choi YM, Kang BG, Yoon YS, et al. A clinical study of decrease appetite effects by aromatherapy using foeniculum vulgare mill (fennel) to female obese patients. J Korean Orient Assoc Stud Obes. 2005; 5:9–20.
10. Puska P, Korpelainen V, Høie LH, Skovlund E, Smerud KT. Isolated soya protein with standardised levels of isoflavones, cotyledon soya fibres and soya phospholipids improves plasma lipids in hypercholesterolaemia: a double-blind, placebo-controlled trial of a yoghurt formulation. Br J Nutr. 2004; 91:393–401.
11. Arjmandi BH, Lucas EA, Khalil DA, Devareddy L, Smith BJ, McDonald J, et al. One year soy protein supplementation has positive effects on bone formation markers but not bone density in postmenopausal women. Nutr J. 2005; 4:8.
12. Sites CK, Cooper BC, Toth MJ, Gastaldelli A, Arabshahi A, Barnes S. Effect of a daily supplement of soy protein on body composition and insulin secretion in postmenopausal women. Fertil Steril. 2007; 88:1609–1617.
13. Garrido A, De la, Hirsch S, Valladares L. Soy isoflavones affect platelet thromboxane A2 receptor density but not plasma lipids in menopausal women. Maturitas. 2006; 54:270–276.
14. Weickert MO, Reimann M, Otto B, Hall WL, Vafeiadou K, Hallund J, et al. Soy isoflavones increase preprandial peptide YY (PYY), but have no effect on ghrelin and body weight in healthy postmenopausal women. J Negat Results Biomed. 2006; 5:11.
15. Zhang YB, Chen WH, Guo JJ, Fu ZH, Yi C, Zhang M, et al. Soy isoflavone supplementation could reduce body weight and improve glucose metabolism in non-Asian postmenopausal women-a meta-analysis. Nutrition. 2013; 29:8–14.
16. Machado AM, de Paula H, Cardoso LD, Costa NM. Effects of brown and golden flaxseed on the lipid profile, glycemia, inflammatory biomarkers, blood pressure and body composition in overweight adolescents. Nutrition. 2015; 31:90–96.
Full Text Links
  • JMM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr