J Clin Neurol.  2018 Jan;14(1):104-106. 10.3988/jcn.2018.14.1.104.

Rapid Progression of Bilateral Vestibulopathy Due to Metastatic Lung Cancer

• Kim SH
• Kim HJ
• Kim JS

• KMID: 2399608
• DOI: http://doi.org/10.3988/jcn.2018.14.1.104

Abstract

No abstract available.

MeSH Terms

Lung Neoplasms*
Lung*

Figure

• 

  Fig. 1 A: The vestibulo-ocular reflex (VOR) gain values are decreased for left horizontal (HC, 0.1, normal range ≥0.8) and both posterior canals (PCs, 0.3 for the right PC, and 0.1 for the left PC, normal range ≥0.7), but normal for right horizontal and both anterior canals (ACs, 1.0 for the right HC, 0.9 for the right AC, and 0.8 for the left AC, normal range ≥0.7). Overt saccades are found for these canals with decreased VOR gains, while covert saccades are observed during stimulation of the right PC and left AC. B: Caloric tests show bilaterally reduced responses with the summated slow phase velocities (SPVs) of the induced nystagmus at 14°/s (8°/s in the right ear, 6°/s in the left ear). C: Video head impulse tests one week later document reduced VOR gains and overt catch-cup saccades for all six semicircular canals (0.2 for the right HC, 0.1 for the left HC, 0.6 for the right AC, 0.4 for the left AC, 0.1 for the right PC, 0.0 for the left PC). D: Brain MRIs reveals nodular gadolinium enhancements within both internal auditory canals (arrows) in addition to increased signals in the cerebellar vermis (arrowheads). ACs: anterior canals, HC: horizontal canal, PCs: posterior canals, SPV: slow phase velocity, VOR: vestibulo-ocular reflex.

Reference

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