J Korean Orthop Assoc.  2005 Feb;40(1):44-49.

Factors Influencing the Recurrence of a Giant Cell Tumor of the Bone

• Kim HS
• Kim SH
• Shin KH
• Hahn SB

Abstract

PURPOSE
The aim of this study was to evaluate the recurrence rates of a giant cell tumor of the bone an determine what, if any, patient factors, tumor characteristics and surgical treatments correlate with the incidence of a local recurrence. MATERIALS AND METHODS: The records of fifty two cases who were diagnosed with a giant cell tumor of the bone between March 1992 and March 2001 and were could be followed up for at least 2 years were analysed retrospectively. This study reviewed the clinical characters, and the treatment method, recurrence, complication, the result of the follow-up. A Fisher' exact test was carried out to analyse the statistics. RESULTS: Sixteen patients (31%)had a local recurrence. The average time to recurrence was 17 months. All but case one recurred within 2 years after receiving surgical treatment. There was no significant differences in the recurrence rates based on the following variables: gender, tumor location, Campanacci grade, the presence of a pathologic fracture, primary versus recurrent tumor at presentation, resection margin, the use of a bone graft, internal fixation or polymethylmethacrylate. CONCLUSION: The clinical characters and methods of treatment were not correlated with a local recurrence. Most recurrences of a giant cell tumor can be expected within the first two to three years. Therefore the patient needs to be followed up in that period and longer for the a late recurrence and pulmonary metastasis.

Keyword

Giant cell tumor of the bone; The incidence of a recurrence

MeSH Terms

Follow-Up Studies
Fractures, Spontaneous
Giant Cell Tumors*
Giant Cells*
Humans
Incidence
Neoplasm Metastasis
Polymethyl Methacrylate
Recurrence*
Retrospective Studies
Transplants
Polymethyl Methacrylate