Korean J Thorac Cardiovasc Surg.  2017 Dec;50(6):415-423. 10.5090/kjtcs.2017.50.6.415.

Lobectomy versus Sublobar Resection in Non-Lepidic Small-Sized Non-Small Cell Lung Cancer

• Namkoong M
• Moon Y
• Park JK

• KMID: 2398371
• DOI: http://doi.org/10.5090/kjtcs.2017.50.6.415

Abstract

BACKGROUND
Recently, many surgeons have chosen sublobar resection for the curative treatment of lung tumors with ground-glass opacity, which is a hallmark of lepidic lung cancer. The purpose of this study was to evaluate the oncological results of sublobar resection for non-lepidic lung cancer in comparison with lobectomy.
METHODS
We conducted a retrospective chart review of 328 patients with clinical N0 non-small cell lung cancer sized ≤2 cm who underwent curative surgical resection from January 2009 to December 2014. The patients were classified on the basis of their lesions into non-lepidic and lepidic groups. The survival rates following lobectomy and sublobar resection were compared within each of these 2 groups.
RESULTS
The non-lepidic group contained a total of 191 patients. The 5-year recurrence-free survival rate was not significantly different between patients who received sublobar resection or lobectomy in the non-lepidic group (80.1% vs. 79.2%, p=0.822) or in the lepidic group (100% vs. 97.4%, p=0.283). Multivariate analysis indicated that only lymphatic invasion was a significant risk factor for recurrence in the non-lepidic group. Sublobar resection was not a risk factor for recurrence in the non-lepidic group.
CONCLUSION
The oncological outcomes of sublobar resection and lobectomy in small-sized non-small cell lung cancer did not significantly differ according to histological type.

Keyword

Lung neoplasms; Thoracic surgery; Pathology; Lung lobectomy; Pathology

MeSH Terms

Carcinoma, Non-Small-Cell Lung*
Humans
Lung
Lung Neoplasms
Multivariate Analysis
Pathology
Recurrence
Retrospective Studies
Risk Factors
Surgeons
Survival Rate
Thoracic Surgery