Imaging Sci Dent.  2017 Dec;47(4):281-284. 10.5624/isd.2017.47.4.281.

Magnetic resonance imaging appearance of foreign-body granulomatous reactions to dermal cosmetic fillers

• Costa AL
• Caliento R
• da Rocha G
• Gomes JP
• Mansmith A
• de Freitas CF
• Braz-Silva PH

• KMID: 2397844
• DOI: http://doi.org/10.5624/isd.2017.47.4.281

Abstract

Foreign body granulomas can develop after the injection of various cosmetic filling materials into the facial area to flatten wrinkles. Clinically, reactive lesions are easily mistaken for soft-tissue neoplasms or cysts. This report presents a case of foreign body granuloma in a 52-year-old female patient complaining of a painless swelling in the nasolabial region. Both clinical and histological features are described, underscoring the diagnostic role of magnetic resonance imaging findings.

Keyword

Magnetic Resonance Imaging; Granuloma, Foreign-Body; Dermal Filllers

MeSH Terms

Female
Granuloma, Foreign-Body
Humans
Magnetic Resonance Imaging*
Middle Aged

Figure

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  Fig. 1 Swelling and mild redness is seen of the right nasolabial fold.

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  Fig. 2 A. An axial T2-weighted MR image shows a cluster of low-intensity fluid collection. B. A coronal T1-weighted spectral pre-saturation with inversion recovery (SPIR) image with contrast surrounded by a thin hypo-intense capsule in the nasolabial fold. C. A T1-weighted sagittal image reveals an iso-hypointense collection.

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  Fig. 3 Histopathological view (hematoxylin and eosin stain; original magnification A. 100×. B. 400×): A well-circumscribed granulomatous reaction without necrosis, showing a large number of multinucleated giant cells with peripheral disposition of the nuclei associated with areas without substance, indicating foreign body particles (*).

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