Asia Pac Allergy.  2015 Jul;5(3):136-144. 10.5415/apallergy.2015.5.3.136.

Chronic cough: an Asian perspective. Part 1: Epidemiology

Affiliations
  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea. addchang@snu.ac.kr
  • 2Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 110-799, Korea.
  • 3Department of Cardiovascular and Respiratory Studies, University of Hull and Hull York Medical School, Castle Hill Hospital, Cottingham HU16 5JQ, UK.
  • 4Division of Allergy and Clinical Immunology, Department of Medicine, Faculty of Medicine, Allergy and Clinical Immunology Research Group, Chulalongkorn University, Bangkok 10330, Thailand.
  • 5Department of Internal Medicine, Pusan National University School of Medicine, Yangsan 626-700, Korea.
  • 6Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam 463-707, Korea.

Abstract

Asia is one of the most diverse and dynamic continents. Due to recent rapid industrialisation and urbanisation, morbidity patterns are likely to be diverse in Asian populations. Chronic cough is a disease condition resulting from host-environmental interactions, and is associated with a high global epidemiological burden. However, the underlying epidemiology remains unclear, particularly in Asia. We performed a literature search to identify peer-reviewed articles on chronic cough in community-based adult Asian populations that have been published between January 2000 and June 2015. In this review, we aim to examine the epidemiological characteristics and determinants of chronic cough in several geographical areas of Asia.

Keyword

Cough; Epidemiology; Risk Factors; Asia

MeSH Terms

Adult
Asia
Asian Continental Ancestry Group*
Cough*
Epidemiology*
Humans
Risk Factors

Figure

  • Fig. 1 Schematic representation of epidemiological determinants of chronic cough in Asia based on findings from general adult population surveys. Exposure to environmental pollutants and irritants is a risk factor for acute and chronic cough, which may be particularly important in rapidly developing countries. Infection, such as pulmonary tuberculosis or paragonimiasis, is a frequent cause of chronic cough in some areas. Host factors, such as older age, female sex, allergy, or comorbidities, may also predispose individuals to chronic cough hypersensitivity. Angiotensin converting enzyme (ACE) inhibitor-induced cough is more frequent in Asian than in Caucasian populations. Dietary habits may also influence the incidence of chronic cough.


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