Asia Pac Allergy.  2015 Oct;5(4):197-202. 10.5415/apallergy.2015.5.4.197.

A study of treatment adherence and quality of life among adults with chronic urticaria in Singapore

Affiliations
  • 1Department of Medicine, National University Hospital, Singapore 119074, Singapore. jun_khee_heng@nuhs.edu.sg
  • 2Department of Preventive Medicine, National University Hospital, Singapore 119074, Singapore.

Abstract

BACKGROUND
Chronic urticaria is a common skin condition that causes significant impact on patient's quality of life.
OBJECTIVE
The purpose of the study was to assess adherence to therapy and quality of life of patients with chronic urticaria. We also aimed to study the relationship of medication adherence and quality of life of patients with chronic urticaria.
METHODS
A cross sectional study was conducted with 103 patients from the dermatology clinic of National University Hospital, Singapore. Patients with chronic urticaria were asked to fill out a questionnaire for assessment of adherence to therapy and quality of life. We used the Morisky 8-Item Medication Adherence Scale to categorize adherence as high, medium, low. For assessment of quality of life, we used the validated chronic urticaria quality of life questionnaire (CU-Q2oL) by Bairadani et al.
RESULTS
The highest median scores for the items measuring quality of life were interference with sleep and pruritus. We also observed that the majority of patients (71.9%) had low adherence to medical therapy. No difference in adherence was noted in patients on once daily medication or more frequent dosing. There was no significant difference in the quality of life among patients with low and medium adherence to therapy.
CONCLUSION
Quality of life of patients with chronic urticaria does not depend on the patients' adherence to medications. Dosing frequency does not affect adherence in our study population. It is also important to recognize the symptoms and issues most affecting quality of life of patients with chronic urticaria, so as to improve overall management.

Keyword

Urticaria; Quality of life; Medication adherence; Singapore

MeSH Terms

Adult*
Dermatology
Humans
Medication Adherence
Pruritus
Quality of Life*
Singapore*
Skin
Urticaria*

Cited by  2 articles

Economic Burden of the Inadequate Management of Allergic Rhinitis and Urticaria in Asian Countries Based on the GA2LEN Model
Kanokvalai Kulthanan, Supinda Chusakul, Marysia Tiongco Recto, Ma. Teresita Gabriel, Derrick Chen-Wee Aw, Narayanan Prepageran, Alson Wong, Jern Lin Leong, Henry Foong, Vo Thanh Quang, Torsten Zuberbier
Allergy Asthma Immunol Res. 2018;10(4):370-378.    doi: 10.4168/aair.2018.10.4.370.

Great learning, much networking, and friendship
Yoon-Seok Chang
Asia Pac Allergy. 2015;5(4):191-192.    doi: 10.5415/apallergy.2015.5.4.191.


Reference

1. Zuberbier T, Aberer W, Asero R, Bindslev-Jensen C, Brzoza Z, Canonica GW, Church MK, Ensina LF, Gimenez-Arnau A, Godse K, Gonçalo M, Grattan C, Hebert J, Hide M, Kaplan A, Kapp A, Abdul Latiff AH, Mathelier-Fusade P, Metz M, Nast A, Saini SS, Sanchez-Borges M, Schmid-Grendelmeier P, Simons FE, Staubach P, Sussman G, Toubi E, Vena GA, Wedi B, Zhu XJ, Maurer M. European Academy of Allergy and Clinical Immunology. Global Allergy and Asthma European Network. European Dermatology Forum. World Allergy Organization. The EAACI/GA(2) LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update. Allergy. 2014; 69:868–887.
2. Grob JJ, Revuz J, Ortonne JP, Auquier P, Lorette G. Comparative study of the impact of chronic urticaria, psoriasis and atopic dermatitis on the quality of life. Br J Dermatol. 2005; 152:289–295.
Article
3. Morisky DE, Ang A, Krousel-Wood M, Ward HJ. Predictive validity of a medication adherence measure in an outpatient setting. J Clin Hypertens (Greenwich). 2008; 10:348–354.
Article
4. Baiardini I, Pasquali M, Braido F, Fumagalli F, Guerra L, Compalati E, Braga M, Lombardi C, Fassio O, Canonica GW. A new tool to evaluate the impact of chronic urticaria on quality of life: chronic urticaria quality of life questionnaire (CU-QoL). Allergy. 2005; 60:1073–1078.
5. Yun J, Katelaris CH, Weerasinghe A, Adikari DB, Ratnayake C. Impact of chronic urticaria on the quality of life in Australian and Sri Lankan populations. Asia Pac Allergy. 2011; 1:25–29.
Article
6. O'Donnell BF, Lawlor F, Simpson J, Morgan M, Greaves MW. The impact of chronic urticaria on the quality of life. Br J Dermatol. 1997; 136:197–201.
7. Augustin M, Holland B, Dartsch D, Langenbruch A, Radtke MA. Adherence in the treatment of psoriasis: a systematic review. Dermatology. 2011; 222:363–374.
Article
8. Jones-Caballero M, Pedrosa E, Peñas PF. Self-reported adherence to treatment and quality of life in mild to moderate acne. Dermatology. 2008; 217:309–314.
Article
9. Staab D, Diepgen TL, Fartasch M, Kupfer J, Lob-Corzilius T, Ring J, Scheewe S, Scheidt R, Schmid-Ott G, Schnopp C, Szczepanski R, Werfel T, Wittenmeier M, Wahn U, Gieler U. Age related, structured educational programmes for the management of atopic dermatitis in children and adolescents: multicentre, randomised controlled trial. BMJ. 2006; 332:933–938.
Article
10. Saini SD, Schoenfeld P, Kaulback K, Dubinsky MC. Effect of medication dosing frequency on adherence in chronic diseases. Am J Manag Care. 2009; 15:e22–e33.
Full Text Links
  • APA
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2023 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr