Asia Pac Allergy.  2017 Jul;7(3):179-181. 10.5415/apallergy.2017.7.3.179.

Is nonhomogeneous expression of tissue mast cells or allergen specific IgEs bound to tissue mast cells possible?

• Türk M
• BahçecioÄŸlu SN
• Yılmaz I

• KMID: 2396943
• DOI: http://doi.org/10.5415/apallergy.2017.7.3.179

Abstract

Skin prick tests (SPTs) are widely used to demonstrate an IgE-mediated hypersensitivity reaction to a specific allergen. However, local allergic conditions cannot be diagnosed with SPTs. Local specific IgE production was only presented before in mucosal tissues. We present a patient with house dust mite sensitization that had variable SPTs results in different body regions.

Keyword

Skin prick tests; Local allergy; Entopy; Disease mechanism

MeSH Terms

Body Regions
Humans
Hypersensitivity, Immediate
Immunoglobulin E
Mast Cells*
Mucous Membrane
Pyroglyphidae
Skin
Immunoglobulin E

Figure

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  Fig. 1 Skin prick tests (SPTs) results (numbers 7 and 8) of the dorsal skin of the patient. Dermatophagoides pteronyssinus (DP) and Dermatophagoides farina (DF) of panel B were negative and DP of panel A was positive. GH, panel A histamine; GN, panel A negative control; G3, panel A DF; G4, panel A DP; AH, panel B histamine; AN, panel B negative control; A3, panel B DF; A4, panel B DP.

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