J Liver Cancer.
2017 Sep;17(2):182-185. 10.17998/jlc.17.2.182.
A Case of Successful Living Donor Liver Transplantation after Down-staging of Hepatocellular Carcinoma with the Beyond Milan Criteria by Radioembolization, Hepatic Arterial Infusion Chemotherapy, and Stereotactic Body Radiation Therapy
- Affiliations
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- 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. dyk1025@yuhs.ac
- 2Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
- 3Yonsei Liver Center, Severance Hospital, Seoul, Korea.
- 4Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.
- KMID: 2396575
- DOI: http://doi.org/10.17998/jlc.17.2.182
Abstract
- Liver transplantation for patients with hepatocellular carcinoma (HCC) within the Milan criteria generally yields a 4-year overall survival rate of 75% and 4-year recurrence free survival rate of 83%. But, many HCC patients present with the disease beyond the Milan criteria. On the other hands, the overall survival of patients with advanced HCC with portal vein invasion is very poor. We report a case of successful living donor liver transplantation for advanced HCC with portal vein invasion by down-staging through radioembolization, hepatic arterial infusion chemotherapy, and stereotactic body radiation therapy.
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