J Pathol Transl Med.  2017 Nov;51(6):528-532. 10.4132/jptm.2017.09.12.

History and Practice of Thyroid Fine-Needle Aspiration in China, Based on Retrospective Study of the Practice in Shandong University Qilu Hospital

• Liu Z
• Liu D
• Ma B
• Zhang X
• Su P
• Chen L
• Zeng Q

• KMID: 2396534
• DOI: http://doi.org/10.4132/jptm.2017.09.12

Abstract

Cytology in China developed from nothing and underwent a long journey from gynecologic cytology to that of all organs, laying a solid foundation for new developments in the 21st century. Thyroid fine-needle aspiration (FNA) was primarily developed in an endocrinology department and then in the clinical laboratory department or pathology department in the 1970-80s. Wrights staining is popular in endocrine and clinical laboratory departments, while hematoxylin and eosin staining is common in pathology. Liquid based cytology is not common in thyroid FNA cytology, while BRAF(V600E) mutation analysis has been the most popular molecular test. The history and practice of thyroid FNA practice in China were reviewed based on retrospective study of the practice in Qilu Hospital of Shandong University.

Keyword

Thyroid fine needle aspiration; Practice; China; Qilu Hospital

MeSH Terms

Biopsy, Fine-Needle*
China*
Endocrinology
Eosine Yellowish-(YS)
Hematoxylin
Pathology
Retrospective Studies*
Thyroid Gland*
Eosine Yellowish-(YS)
Hematoxylin

Figure

• 

  Fig. 1. (A) Cytology of hyalinizing trabecular tumor. The thin green arrow shows nuclear groove, and the thin blue arrow shows pseudoinclusion. The arrowhead shows filament-like hyalinizing material between the tumor cells. (B) Histology of hyalinizing trabecular tumor. The thin green arrow shows nuclear groove, and the thin blue arrow shows pseudoinclusion. The arrowhead shows hyalinizing material around the cell nests.

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