Ann Dermatol.  2017 Apr;29(2):229-232. 10.5021/ad.2017.29.2.229.

A Case of Primary Cutaneous Gamma-Delta T-Cell Lymphoma with Pautrier Microabscess

• Kato K
• Namiki T
• Ueno M
• Iikawa M
• Tokoro S
• Nishizawa
• Yamamoto K
• Miura K
• Yokozeki H

• KMID: 2394851
• DOI: http://doi.org/10.5021/ad.2017.29.2.229

Abstract

No abstract available.

MeSH Terms

Lymphoma, T-Cell*
T-Lymphocytes*

Figure

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  Fig. 1 (A) Multiple erythematous tumors and plaques on the patient's trunk. The largest tumor was observed at the right lower abdomen. (B) Multiple erythematous tumors on the lower extremities.

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  Fig. 2 (A) Histology of a biopsy specimen of an erythematous plaque showing focal infiltrates of atypical lymphocytes in the dermis. The dotted boxes indicate the locations shown at higher magnification in Fig. 1B and 1C (H&E, ×20). (B) Infiltrates of atypical lymphocytes intermingled with histiocytes in the dermis (H&E, ×400). (C) Aggregations of atypical lymphocytes as Pautrier's microabscess in the epidermis (H&E, ×400). (D) Flow cytometry analyses of a biopsy specimen from the skin using a CD45/SSC gating procedure. CD45/SSC gated cells with various surface antigens of CD4, CD8, T-cell receptor (TCR)-αβ, TCR-γδ shown in two dot plots. (E) Immunohistochemistry of a biopsy specimen from the skin showing a positive reaction for CγM1 (×400). (F) Immunohistochemistry of a biopsy specimen from the skin showing a negative reaction for βF1 (×400). (G) Immunohistochemistry from a lymph node showing a positive reaction for CγM1 (×400).

Reference

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