Ann Dermatol.  2017 Apr;29(2):223-225. 10.5021/ad.2017.29.2.223.

Morgellons Disease

Affiliations
  • 1Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea. kyuhkim@snu.ac.kr

Abstract

Morgellons disease is a rare disease with unknown etiology. Herein, we report the first case of Morgellons disease in Korea. A 30-year-old woman presented with a 2-month history of pruritic erythematous patches and erosions on the arms, hands, and chin. She insisted that she had fiber-like materials under her skin, which she had observed through a magnifying device. We performed skin biopsy, and observed a fiber extruding from the dermal side of the specimen. Histopathological examination showed only mild lymphocytic infiltration, and failed to reveal evidence of any microorganism. The polymerase chain reaction for Borrelia burgdorferi was negative in her serum.

Keyword

Asian continental ancestry group; Borrelia burgdorferi; Morgellons disease

MeSH Terms

Adult
Arm
Asian Continental Ancestry Group
Biopsy
Borrelia burgdorferi
Chin
Female
Hand
Humans
Korea
Morgellons Disease*
Nerve Fibers, Myelinated
Polymerase Chain Reaction
Rare Diseases
Skin

Figure

  • Fig. 1 Photographs taken by the patient with a magnifying device (×200): black, brown, and red fibers were tangled on the erosive skin.

  • Fig. 2 Erythematous patch and macules on the palm, hand dorsum, and chin.

  • Fig. 3 A single black fiber extruding from the specimen's dermal side.

  • Fig. 4 Histopathology of the specimen. Mild superficial perivascular lymphocytic infiltration without any specific material (H&E, ×100).


Cited by  2 articles

Morgellons Disease: Truth & Belief
Luca Roncati, Francesco Piscioli
Ann Dermatol. 2018;30(3):361-362.    doi: 10.5021/ad.2018.30.3.361.

Morgellons Disease: a Manifestation of Psychiatric Disorder
Da-Ae Yu, Jungyoon Ohn, Kyu Han Kim
Ann Dermatol. 2018;30(3):362-363.    doi: 10.5021/ad.2018.30.3.362.


Reference

1. Savely VR, Leitao MM, Stricker RB. The mystery of Morgellons disease: infection or delusion? Am J Clin Dermatol. 2006; 7:1–5.
2. Pearson ML, Selby JV, Katz KA, Cantrell V, Braden CR, Parise ME, et al. Clinical, epidemiologic, histopathologic and molecular features of an unexplained dermopathy. PLoS One. 2012; 7:e29908.
Article
3. Middelveen MJ, Bandoski C, Burke J, Sapi E, Filush KR, Wang Y, et al. Exploring the association between Morgellons disease and Lyme disease: identification of Borrelia burgdorferi in Morgellons disease patients. BMC Dermatol. 2015; 15:1.
Article
4. Middelveen MJ, Burugu D, Poruri A, Burke J, Mayne PJ, Sapi E, et al. Association of spirochetal infection with Morgellons disease. F1000Re. 2013; 2:25.
Article
5. Robles DT, Olson JM, Combs H, Romm S, Kirby P. Morgellons disease and delusions of parasitosis. Am J Clin Dermatol. 2011; 12:1–6.
Article
6. Söderfeldt Y, Groß D. Information, consent and treatment of patients with Morgellons disease: an ethical perspective. Am J Clin Dermatol. 2014; 15:71–76.
Article
7. Hylwa SA, Foster AA, Bury JE, Davis MD, Pittelkow MR, Bostwick JM. Delusional infestation is typically comorbid with other psychiatric diagnoses: review of 54 patients receiving psychiatric evaluation at Mayo Clinic. Psychosomatics. 2012; 53:258–265.
Article
8. Foster AA, Hylwa SA, Bury JE, Davis MD, Pittelkow MR, Bostwick JM. Delusional infestation: clinical presentation in 147 patients seen at Mayo Clinic. J Am Acad Dermatol. 2012; 67:673.e1–673.e10.
Article
9. Gartner AM, Dolan SL, Stanford MS, Elkins GR. Hypnosis in the treatment of Morgellons disease: a case study. Int J Clin Exp Hypn. 2011; 59:242–249.
10. Reid EE, Lio PA. Successful treatment of Morgellons disease with pimozide therapy. Arch Dermatol. 2010; 146:1191–1193.
Article
11. Middelveen MJ, Mayne PJ, Kahn DG, Stricker RB. Characterization and evolution of dermal filaments from patients with Morgellons disease. Clin Cosmet Investig Dermatol. 2013; 6:1–21.
Full Text Links
  • AD
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr