Korean J Fam Med.  2016 Jul;37(4):221-227. 10.4082/kjfm.2016.37.4.221.

The Association between Vitamin D and Health-Related Quality of Life in Korean Adults

• Kim JS
• Choi YE
• Baek JK
• Cho HJ
• Kim YS

• KMID: 2391711
• DOI: http://doi.org/10.4082/kjfm.2016.37.4.221

Abstract

BACKGROUND
We examined the relationship between vitamin D status and health-related quality of life, and explored other related factors in the general Korean population.
METHODS
We used data from the 2007-2012 Korea National Health and Nutrition Examination Survey on 14,104 adults, aged 20-49 years, who had consented to serum vitamin D measurement and answered health-related quality of life questions. EuroQol-5 was used for measurement. Serum vitamin D levels were measured at intervals of 0-9.99, 10-19.99, 20-29.99, and ≥30 ng/mL.
RESULTS
Participants with higher serum vitamin D (serum 25-hydroxyvitamin D) levels were significantly less likely to report problems with depression and anxiety. After adjustment for age, gender, income level, education level, marital status, alcohol consumption, smoking status, and the existence of depressive disorders, the odds ratio for reporting a problem with depression and anxiety was 0.60 (95% confidence interval [CI], 0.39-0.91). The odds ratio for the prevalence of any problem was 0.69 (95% CI, 0.53-0.89) before adjustment, but was not statistically significant after adjustment. No significant associations were observed for problems with mobility, self-care, usual activity, or pain and discomfort.
CONCLUSION
This is the first study to examine the associations between vitamin D and health-related quality of life for the general Korean population. Vitamin D status was not significantly associated with the dimensions of EuroQol-5 except for depression and anxiety problems.

Keyword

Vitamin D; Quality of Life; Depression; Anxiety

MeSH Terms

Adult*
Alcohol Drinking
Anxiety
Depression
Depressive Disorder
Education
Humans
Korea
Marital Status
Nutrition Surveys
Odds Ratio
Prevalence
Quality of Life*
Self Care
Smoke
Smoking
Vitamin D*
Vitamins*
Smoke
Vitamin D
Vitamins