Ann Dermatol.  2002 Sep;14(3):174-177. 10.5021/ad.2002.14.3.174.

A Case of Granuloma Faciale Showing Unusual Histopathological findings

• Lee MW
• Kang SK
• Jee MS
• Lee MW
• Choi JH
• Sung KJ
• Moon KC
• Koh JK

• KMID: 2391077
• DOI: http://doi.org/10.5021/ad.2002.14.3.174

Abstract

Granuloma faciale is an uncommon localized form of small-vessel vasculitis characterized by single or multiple lesions on the face in middle-aged whites, especially males. Histopathological examination demonstrates a dense polymorphous cellular infiltrate consisting of neutrophils, eosinophils, lymphocytes and histiocytes in the upper two thirds of the dermis. A characteristic subepidermal Grenz zone separates the infiltrate from the epidermis. We report a case of granuloma faciale, showing interesting evidence of palisaded granuloma-like pattern in the serial biopsy specimen at 3-year interval.

Keyword

Granuloma faciale; Palisaded granuloma

MeSH Terms

Biopsy
Dermis
Eosinophils
Epidermis
Granuloma*
Histiocytes
Humans
Lymphocytes
Male
Neutrophils
Vasculitis