J Stroke.  2017 May;19(2):143-151. 10.5853/jos.2017.00626.

Diagnostic and Therapeutic Strategies for Acute Intracranial Atherosclerosis-related Occlusions

Affiliations
  • 1Department of Neurology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea. jinsoo22@gmail.com
  • 2Department of Neurology, Asan Medical Center, University of Ulsan, Seoul, Korea.

Abstract

Intracranial atherosclerosis-related occlusion (ICAS-O) is frequently encountered at the time of endovascular revascularization treatment (ERT), especially in Asian countries. However, because baseline angiographic findings are similar between ICAS-O and embolism-related occlusion (EMB-O), it is difficult to differentiate the etiologies before the ERT procedure. Moreover, despite successful randomized trials on ERT, results from studies examining the optimal treatment protocol in ICAS-O patients remain unclear. In this review, we describe the clinical and imaging factors that may possibly differentiate ICAS-O from EMB-O. We will also discuss some current hurdles for treating ICAS-O in the hyperacute period and suggest the optimal ERT strategy for ICAS-O patients.

Keyword

Intracranial arteriosclerosis; Intracranial thrombosis; Intracranial embolism; Endovascular procedures; Diagnosis; Therapy

MeSH Terms

Asian Continental Ancestry Group
Clinical Protocols
Diagnosis
Endovascular Procedures
Humans
Intracranial Arteriosclerosis
Intracranial Embolism
Intracranial Thrombosis
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