J Korean Neurol Assoc.  2017 Aug;35(3):170-172. 10.17340/jkna.2017.35.3.12.

Bullous Pemphigoid Associated with Cerebral Infarction: Hypereosinophilia as a Possible Mechanism

• Yang W
• Jeong HG
• Lee SH

• KMID: 2388639
• DOI: http://doi.org/10.17340/jkna.2017.35.3.12

Abstract

Bullous pemphigoid (BP) is an autoimmune skin disease, which manifests as subepidermal blisters with severe itching. BP has been reported to be associated with a higher prevalence of cerebrovascular diseases in population-based studies. However, the mechanism of cerebral infarction from BP has not been elucidated yet. We hereby suggest that the missing link between BP and cerebral infarction may be eosinophil, through a case of a woman with multifocal embolic infarction.

Keyword

Stroke; Bullous pemphigoid; Eosinophil; Hypereosinophilia

MeSH Terms

Blister
Cerebral Infarction*
Cerebrovascular Disorders
Eosinophils
Female
Humans
Infarction
Pemphigoid, Bullous*
Prevalence
Pruritus
Skin Diseases
Stroke