J Korean Neurol Assoc.  2017 Aug;35(3):162-165. 10.17340/jkna.2017.35.3.10.

Hyponatremia during Acyclovir Treatment of Bell's Palsy

Affiliations
  • 1Department of Neurology, Soonchunhyang University Seoul Hospital, Seoul, Korea. kblee@schmc.ac.kr

Abstract

A 61-year-old woman with chronic kidney disease presented with general weakness and a confused mentality. Two days before admission she had been diagnosed as Bell's palsy at an outpatient clinic, and started to take oral prednisolone and acyclovir. A blood test at admission revealed hyponatremia (128 mmol/L). After withdrawing acyclovir, her plasma sodium levels began to increase, returning to normal 2 weeks later. This case could provide further evidence for a causal relationship between acyclovir and hyponatremia.

Keyword

Acyclovir; Hyponatremia; Bell's palsy

MeSH Terms

Acyclovir*
Ambulatory Care Facilities
Bell Palsy*
Female
Hematologic Tests
Humans
Hyponatremia*
Middle Aged
Plasma
Prednisolone
Renal Insufficiency, Chronic
Sodium
Acyclovir
Prednisolone
Sodium
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