Soonchunhyang Med Sci.  2016 Dec;22(2):129-131. 10.0000/sms.2016.22.2.129.

Meigs' Syndrome with Elevated Cancer Antigen 125

• Park HN
• Kim SG
• Kim YS

• KMID: 2387005
• DOI: http://doi.org/10.0000/sms.2016.22.2.129

Abstract

Meigs' syndrome is a fibroma associated with ascites and/or pleural effusion and several cases have been reported in association with elevated serum cancer antigen (CA) 125 level. We report here on a 72-year-old woman who presented with palpable huge pelvic mass. Abdomen and pelvic computed tomography showed a heterogenous huge pelvic mass measuring 210×110 mm with large amount of ascites. No pleural effusion was detected on chest X-ray. CA 125 level was 327 IU/mL. The patient underwent laparotomy during which a mass measuring 210×110 mm was detected in her right ovary with 1,000 mL of ascites. Histology showed ovarian fibroma. We performed total abdominal hysterectomy with bilateral salpingo-oophorectomy. Postmenopausal woman with ovarian tumor, ascites, and elevated CA 125 may indicate malignant ovarian tumor, but Meigs' syndrome must be considered as differential diagnosis.

Keyword

Meigs' syndrome; Fibroma; Ascites; CA-125 antigen

MeSH Terms

Abdomen
Aged
Ascites
CA-125 Antigen
Diagnosis, Differential
Female
Fibroma
Humans
Hysterectomy
Laparotomy
Meigs Syndrome*
Ovary
Pleural Effusion
Thorax
CA-125 Antigen