Soonchunhyang Med Sci.  2016 Dec;22(2):112-114. 10.0000/sms.2016.22.2.112.

Antimicrobial Activity of Medizyme-Plus, Developed for Cleansing Prior to Disinfection/Sterilization

• Bang HI
• Choi TY

• KMID: 2387001
• DOI: http://doi.org/10.0000/sms.2016.22.2.112

Abstract

OBJECTIVE
Disinfectants are essential for public health and environmental hygiene. The aim of this study was to investigate the in vitro antimicrobial activity of Medizyme-Plus (Soosan Co. Ltd., Seongnam, Korea) developed for cleansing prior to disinfection/ster-ilization, against bacteria and yeasts.
METHODS
Clinical isolates were exposed to Medizyme-Plus (a product containing quaternary ammonium and a protease, amylase, and lipase) for various periods (0.5, 1, 2, 5, 10, 15, and 30 minutes). After exposure, the mixtures of isolates and Medizyme-Plus were inoculated into tryptic soy broths. To enumerate the surviving bacteria or yeasts, treated isolates were inoculated onto solid agar media (blood agar, MacConkey agar, and Sabouraud dextrose agar) and cultured at 35℃.
RESULTS
All strains of bacteria and yeasts showed a 5-log10 reduction within 0.5 minutes of exposure to Medizyme-Plus.
CONCLUSION
Medizyme-Plus can be used as a low-level disinfectant, in addition to cleanser, for hospital infection control. It will be necessary to perform disinfection/sterilization after cleansing with Medizyme-Plus.

Keyword

Disinfectants; Ammonium compounds; Protease

MeSH Terms

Agar
Ammonium Compounds
Amylases
Bacteria
Cross Infection
Disinfectants
Glucose
Gyeonggi-do
Hygiene
In Vitro Techniques
Public Health
Yeasts
Agar
Amylases
Disinfectants
Glucose