J Clin Neurol.  2016 Oct;12(4):515-516. 10.3988/jcn.2016.12.4.515.

Persistent Hyperthermia in a Patient with Aquaporin-4-Antibody-Positive Neuromyelitis Optica Spectrum Disorder

• Hsu CL
• Yeh JH
• Lau CI

• KMID: 2385122
• DOI: http://doi.org/10.3988/jcn.2016.12.4.515

Abstract

No abstract available.

MeSH Terms

Fever*
Humans
Neuromyelitis Optica*

Figure

• 

  Fig. 1 Brain MRI. A: Coronal T2-weighted MRI illustrating hyperintensities in the hypothalamus, optic chiasm, and mammillary bodies. B: Sagittal T1-weighted MRI following gadolinium administration illustrating strong enhancement in the preoptic/anterior hypothalamus (arrow).

Reference

1. Edwards S, Lennox G, Robson K, Whiteley A. Hypothermia due to hypothalamic involvement in multiple sclerosis. J Neurol Neurosurg Psychiatry. 1996; 61:419–420.

2. White KD, Scoones DJ, Newman PK. Hypothermia in multiple sclerosis. J Neurol Neurosurg Psychiatry. 1996; 61:369–375.

3. Wingerchuk DM, Banwell B, Bennett JL, Cabre P, Carroll W, Chitnis T, et al. International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology. 2015; 85:177–189.

4. Chan KH, Tse CT, Chung CP, Lee RL, Kwan JS, Ho PW, et al. Brain involvement in neuromyelitis optica spectrum disorders. Arch Neurol. 2011; 68:1432–1439.

5. Pittock SJ, Weinshenker BG, Lucchinetti CF, Wingerchuk DM, Corboy JR, Lennon VA. Neuromyelitis optica brain lesions localized at sites of high aquaporin 4 expression. Arch Neurol. 2006; 63:964–968.

6. Benarroch EE. Thermoregulation: recent concepts and remaining questions. Neurology. 2007; 69:1293–1297.

7. Pu S, Long Y, Yang N, He Y, Shan F, Fan Y, et al. Syndrome of inappropriate antidiuretic hormone secretion in patients with aquaporin-4 antibody. J Neurol. 2015; 262:101–107.

8. Yamasaki K, Horiuchi I, Minohara M, Osoegawa M, Kawano Y, Ohyagi Y, et al. Hyperprolactinemia in optico-spinal multiple sclerosis. Intern Med. 2000; 39:296–299.