Myoepithelial Carcinoma Arising within an Adenomyoepithelioma of the Breast: A Case Report
- Affiliations
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- 1Department of Radiology, Anam Hospital, Korea University College of Medicine, Seoul, Korea. krcho@korea.ac.kr
- 2Department of Radiology, Ansan Hospital, Korea University College of Medicine, Ansan, Korea.
- 3Department of Radiology, Guro Hospital, Korea University College of Medicine, Seoul, Korea.
- 4Department of Pathology, Anam Hospital, Korea University College of Medicine, Seoul, Korea.
- KMID: 2384732
- DOI: http://doi.org/10.3348/jksr.2017.77.1.27
Abstract
- Adenomyoepithelioma of the breast is a rare tumor. A myoepithelial carcinoma arising within an adenomyoepithelioma is even more unusual. There are a limited number of reports discussing myoepithelial carcinoma; most of them describe pathological findings, but not imaging findings. We present a case of a 55-year-old woman who had a screen-detected myoepithelial carcinoma arising within an adenomyoepithelioma in her right breast. Upon the completion of a mammography and sonography an oval shaped mass with an indistinct margin in the upper portion of the right breast had been seen. It as appeared to be a spiculated, irregular-shaped, peripheral-enhancing mass on an MRI. On sonography-guided biopsy, an epithelial-myothelial tumor was confirmed, and the possibility of myoepithelial carcinoma was suggested. Breast-conserving surgery with a sentinel lymph node dissection was performed, and a pathological examination revealed a myoepithelial carcinoma arising within an adenomyoepithelioma.
MeSH Terms
Figure
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Fig. 1 A 55-year-old woman with myoepithelial carcinoma arising within adenomyoepithelioma. A. Screening mammography shows a 2 cm-sized, oval-shaped, isodense mass with indistinct margins (arrows) in the 12 o'clock direction of the right breast. B. Breast sonography shows an indistinct, oval, hypoechoic mass (arrow) seen in the right upper breast. There is no observed abnormal axillary lymphadenopathy. C. On MRI, axial fat-saturated T1-weighted subtraction image with post-contrast gadolinium injection shows an irregular mass with spiculated margins and rim enhancement (arrow) in the right upper mid-to-outer portion. D. On axial fat-saturated T2-weighted image, the mass was hyperintense (arrow). On dynamic study (not shown), this mass shows initial fast-enhancement and delayed plateau pattern. E. On histological examination (hematoxylin and eosin stain, × 100), the tumor shows a relatively uniform admixture of scattered, glandular, epithelial-lined spaces, and surrounding spindle and epithelioid myoepithelial-cell proliferation. F. On immunostaining (SMA, × 200), the myoepithelial cells are immunoreactive for SMA. SMA = smooth muscle actin
Reference
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