J Korean Neuropsychiatr Assoc.
2011 Sep;50(5):347-353.
Pathogenesis of Post-Stroke Depression : A Bio-Psycho-Social Integrative Model
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- 1Department of Psychiatry, Chonnam National University Medical School and Depression Clinical Research Center, Chonnam National University Hospital, Gwangju, Korea. jmkim@chonnam.ac.kr
Abstract
- Depression is common after a stroke and has adverse effects on both the course and prognosis. A proper understanding on the pathogenetic mechanisms of post-stroke depression (PSD) is the first step in the treatment of PSD. PSD should not be considered a purely organic neurological mood syndrome but rather the consequence of a complex interaction model of biological, psychological, and social factors. Based on the pathogenesis, a bio-psycho-social approach is mandatory in the treatment of PSD. A medical team with an integrative bio-psycho-social view should take a pivotal role in the management of PSD.
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