Obstet Gynecol Sci.  2017 Jan;60(1):74-78. 10.5468/ogs.2017.60.1.74.

Clinicopathologic evaluation of myofibroblastoma: A study in two hospitals

• Kim SK
• Lee JS
• Hong SB
• Lee JR
• Jee BC
• Suh CS
• Kim SH

• KMID: 2383211
• DOI: http://doi.org/10.5468/ogs.2017.60.1.74

Abstract

OBJECTIVE
To report various anatomic locations and clinical characteristics of pathologically proven myofibroblastoma in Koran patients.
METHODS
Pathologic reports of patients who underwent surgeries at two centers between April 2003 and March 2016 were retrieved from the electronic medical record system of the hospital. Pathologic reports were included after performing a search using the keyword "myofibroblastoma".
RESULTS
The cohort consisted of 11 subjects and included eight female and three male individuals. The patients' ages ranged from 9 to 66 years. Tumors were located in the vagina in three patients and presented in the breast in seven patients. One case presented with an abdominal mass. The tumors ranged in mean size from 4.0 to 53.0 mm. Despite a relatively long-term follow-up, no case had evidence of tumor recurrence.
CONCLUSION
We evaluated the various anatomic locations of pathologically proven myofibroblastoma in Korean patients. As an extremely rare tumor, physicians should pay special attention to differential diagnosis. Surgical resection is the preferred method for a cure, and the recurrence rate is extremely low.

Keyword

Anatomic variation; Breast; Genital tract; Neoplasms, muscle tissue

MeSH Terms

Anatomic Variation
Breast
Cohort Studies
Diagnosis, Differential
Electronic Health Records
Female
Follow-Up Studies
Humans
Male
Methods
Neoplasms, Muscle Tissue*
Recurrence
Vagina

Figure

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  Fig. 1 The macroscopic appearance (A) vaginal wall (case 1) and (B) breast (case 10).

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  Fig. 2 Positivity for immunohistochemical staining (×400). (A) Smooth muscle actin, (B) CD34, and (C) desmin.

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