Ann Dermatol.  1999 Oct;11(4):276-279. 10.5021/ad.1999.11.4.276.

Sweet's Syndrome Associated with a Benign IgA Gammopathy

• Kim EH
• Kang H
• Cho SH
• Park YM

• KMID: 2383040
• DOI: http://doi.org/10.5021/ad.1999.11.4.276

Abstract

A 71-year-old woman was presented with 5-year history of recurrent, multiple, painful or tender, erythematous plaques on her lower limbs accompanied by fever and arthralgia. Histopathological findings showed a dense infiltration of mature neutrophils in the upper and mid dermis without leukocytoclastic vasculitis. These clinical and histopathological findings were consistent with Sweet's syndrome. The laboratory investigations demonstrated elevated ESR and IgA gammopathy, but no leukocytosis or neutrophilia. Her eruption revealed good responses to systemic steroid therapy. We herein describe a patient with Sweet's syndrome without leukocytosis, probably associated with a benign IgA gammopathy.

Keyword

Sweet's syndrome; IgA gammopathy; Leukocytosis

MeSH Terms

Aged
Arthralgia
Dermis
Female
Fever
Humans
Immunoglobulin A*
Leukocytosis
Lower Extremity
Neutrophils
Sweet Syndrome*
Vasculitis
Immunoglobulin A