Korean J Thorac Cardiovasc Surg.  2015 Feb;48(1):82-85. 10.5090/kjtcs.2015.48.1.82.

Diffuse Large B-cell Lymphoma Arising from Chronic Tuberculous Empyema

Affiliations
  • 1Department of Thoracic and Cardiovascular Surgery, Chonnam National University Hwasun Hospital, Chonnam National University School of Medicine, Hwasun, Korea. sysong@jnu.ac.kr
  • 2Department of Pathology, Chonnam National University Hospital, Chonnam National University School of Medicine, Korea.
  • 3Department of Thoracic and Cardiovascular Surgery, Cheju Halla General Hospital, Korea.

Abstract

Pyothorax-associated lymphoma is a relatively rare type of lymphoma that occurs in patients who have long histories of tuberculous pleuritis or induced pneumothorax. It is a type of non-Hodgkin's lymphoma of mainly the B-cell phenotype and is strongly associated with Epstein-Barr virus infection. A majority of these cases have been reported in Japan, although some cases have occurred in Western countries. Here, we describe a case of pyothorax-associated lymphoma in a patient with a 30-year history of chronic tuberculous empyema. The patient underwent decortication under the impression of chronic empyema with fistula. The histopathologic diagnosis was a diffuse large B-cell lymphoma associated chronic inflammation.

Keyword

Lung; Empyema; Pyothorax-associated lymphoma

MeSH Terms

B-Lymphocytes
Diagnosis
Empyema
Empyema, Tuberculous*
Fistula
Herpesvirus 4, Human
Humans
Inflammation
Japan
Lung
Lymphoma
Lymphoma, B-Cell*
Lymphoma, Non-Hodgkin
Phenotype
Pleurisy
Pneumothorax
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