J Pathol Transl Med.  2015 Jan;49(1):71-74. 10.4132/jptm.2014.12.14.

Placental Mesenchymal Dysplasia with Fetal Gastroschisis

Affiliations
  • 1Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. jsunkim@skku.edu
  • 2Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

No abstract available.


MeSH Terms

Gastroschisis*

Figure

  • Fig. 1. Radiologic and gross findings. (A) Transabdominal ultrasound at 14+5 weeks of gestation shows a large multicystic honeycomb-like placenta measuring 8.8×5.7 cm with no sign of blood flow within the lesion. (B) The fetus has a crown-rump length of 9.6 cm. (C) The placenta is markedly enlarged with multiple vesicles. (D) The fetus exhibits gastroschisis.

  • Fig. 2. Microscopic findings of the placenta. (A) Cystic vesicles are surrounded by stromal tissue and trophoblasts, indicating cysts in enlarged stem villi. No abnormal trophoblast proliferation is observed. (B) The majority of the enlarged stem villi have abnormal vessels with thickened muscular walls. (C) Some of the villi show mesenchymal cell proliferation. (D) Cytotrophoblasts are diffusely immunopositive for p57KIP2.


Reference

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