J Pathol Transl Med.
2015 Jan;49(1):13-22. 10.4132/jptm.2014.12.26.
Genomic Landscapes of Pancreatic Neoplasia
- Affiliations
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- 1The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA. ldwood@jhmi.edu
- KMID: 2381348
- DOI: http://doi.org/10.4132/jptm.2014.12.26
Abstract
- Pancreatic cancer is a deadly disease with a dismal prognosis. However, recent advances in sequencing and bioinformatic technology have led to the systematic characterization of the genomes of all major tumor types in the pancreas. This characterization has revealed the unique genomic landscape of each tumor type. This knowledge will pave the way for improved diagnostic and therapeutic approaches to pancreatic tumors that take advantage of the genetic alterations in these neoplasms.
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