Epidemiol Health.  2015;37:e2015048. 10.4178/epih/e2015048.

Epidemiological evaluation quality of life in patients suffering from early rheumatoid arthritis: a pragmatic, prospective, randomized, blind allocation controlled of a modular program group intervention

• Yousefi H
• Chopra A
• Farrokhseresht R
• Sarmukaddam S
• Noghabi FA
• Bedekar N
• Madani A

• KMID: 2380685
• DOI: http://doi.org/10.4178/epih/e2015048

Abstract

OBJECTIVES
Epidemiology has taken on new roles in the management of health care services. In this study, we developed a non-pharmacological self-management modular program group intervention and evaluated its efficacy as an adjunct therapy in patients suffering from early rheumatoid arthritis (RA).
METHODS
Patients were randomized to either participate in a non-equivalent intervention group along with the standard of care or only receive standard-of-care treatment at a community rheumatology center. The outcomes measured were a pain visual analog scale (VAS), patient general health (GH) on a VAS, and the Short Form 36 Health Survey version 2 scale measuring quality of life. These parameters were evaluated in the first week to obtain baseline values, and at 20, 32, 48, and 60 weeks to evaluate the efficacy of the intervention group.
RESULTS
The patients were randomized, with 100 patients in the intervention group and 106 in the control group. The intervention and control groups were similar with regard to the percentage of women (86% vs. 89.6%), tobacco usage (25% vs. 19.8%), mean age (42.6±13.2 years vs. 46.6±10.9 years), and disease duration (15.3±6.7 months vs. 14.5±6.6 months). The mean outcomes were significantly different between the two groups, and post-hoc pairwise analysis demonstrated significant deterioration in the control group in contrast to improvement in the intervention group at the second, third, fourth, and fifth evaluations. Improvements were often seen as early as the 12-week and 24-week follow-up visits.
CONCLUSIONS
Epidemiology contributes to the evaluation of how well specific therapies or other health interventions prevent or control health problems. The modular program group intervention implemented in this study appears to be a suitable and feasible method to facilitate much more comprehensive management of early RA in socioeconomically challenged communities.

Keyword

Epidemiological method; Quality of life; Early rheumatoid arthritis

MeSH Terms

Arthritis, Rheumatoid*
Delivery of Health Care
Epidemiologic Methods
Epidemiology
Female
Follow-Up Studies
Health Surveys
Humans
Prospective Studies*
Quality of Life*
Rheumatology
Self Care
Standard of Care
Tobacco
Visual Analog Scale