Ann Dermatol.  2017 Jun;29(3):346-348. 10.5021/ad.2017.29.3.346.

Methotrexate in a Real-World Psoriasis Treatment: Is It Really a Dangerous Medication for All?

• Kim BR
• Ohn J
• Choi CW
• Youn SW

• KMID: 2378538
• DOI: http://doi.org/10.5021/ad.2017.29.3.346

Abstract

No abstract available.

MeSH Terms

Methotrexate*
Psoriasis*
Methotrexate

Reference

1. Edmundson WF, Guy WB. Treatment of psoriasis with folic acid antagonists. AMA Arch Derm. 1958; 78:200–203. PMID: 13558707.

2. Heydendael VM, Spuls PI, Opmeer BC, de Borgie CA, Reitsma JB, Goldschmidt WF, et al. Methotrexate versus cyclosporine in moderate-to-severe chronic plaque psoriasis. N Engl J Med. 2003; 349:658–665. PMID: 12917302.

3. Haustein UF, Rytter M. Methotrexate in psoriasis: 26 years' experience with low-dose long-term treatment. J Eur Acad Dermatol Venereol. 2000; 14:382–388. PMID: 11305380.

4. Weidmann A, Foulkes AC, Kirkham N, Reynolds NJ. Methotrexate toxicity during treatment of chronic plaque psoriasis: a case report and review of the literature. Dermatol Ther (Heidelb). 2014; 4:145–156. PMID: 24942326.

5. Salliot C, van der Heijde D. Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: a systematic literature research. Ann Rheum Dis. 2009; 68:1100–1104. PMID: 19060002.

6. Kivity S, Zafrir Y, Loebstein R, Pauzner R, Mouallem M, Mayan H. Clinical characteristics and risk factors for low dose methotrexate toxicity: a cohort of 28 patients. Autoimmun Rev. 2014; 13:1109–1113. PMID: 25172240.

7. Kalb RE, Strober B, Weinstein G, Lebwohl M. Methotrexate and psoriasis: 2009 National Psoriasis Foundation Consensus Conference. J Am Acad Dermatol. 2009; 60:824–837. PMID: 19389524.

8. Weinstein GD, White GM. An approach to the treatment of moderate to severe psoriasis with rotational therapy. J Am Acad Dermatol. 1993; 28:454–459. PMID: 8445062.

9. Pathirana D, Ormerod AD, Saiag P, Smith C, Spuls PI, Nast A, et al. European S3-guidelines on the systemic treatment of psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2009; 23(Suppl 2):1–70.

10. Maybury CM, Jabbar-Lopez ZK, Wong T, Dhillon AP, Barker JN, Smith CH. Methotrexate and liver fibrosis in people with psoriasis: a systematic review of observational studies. Br J Dermatol. 2014; 171:17–29.